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RefWorks
Reference Manager
BibTeX
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EndNote
-
1.
Molyneux EM, Rochford R, Griffin B, Newton R, Jackson G, Menon G, Harrison CJ, Israels T, Bailey S, 2012. Burkitt's lymphoma. Lancet 379: 1234–1244.
-
2.
Bouvard V, Baan R, Straif K, Grosse Y, Secretan B, El Ghissassi F, Benbrahim-Tallaa L, Guha N, Freeman C, Galichet L, Cogliano V, 2009. A review of human carcinogens: Part B: biological agents. Lancet Oncol 10: 321–322. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19350698. Accessed June 6, 2013.
-
3.
Carpenter LM, Newton R, Casabonne D, Ziegler J, Mbulaiteye S, Mbidde E, Wabinga H, Jaffe H, Beral V, 2008. Antibodies against malaria and Epstein-Barr virus in childhood Burkitt lymphoma: a case-control study in Uganda. Int J Cancer 122: 1319–1323.
-
4.
Mutalima N, Molyneux E, Jaffe H, Kamiza S, Borgstein E, Mkandawire N, Liomba G, Batumba M, Lagos D, Gratrix F, Boshoff C, Casabonne D, Carpenter LM, Newton R, 2008. Associations between Burkitt lymphoma among children in Malawi and infection with HIV, EBV and malaria: results from a case-control study. PLoS One 3: e2505.
-
5.
Aka P, Vila MC, Jariwala A, Nkrumah F, Emmanuel B, Yagi M, Palacpac NM, Periago MV, Neequaye J, Kiruthu C, Tougan T, Levine PH, Biggar RJ, Pfeiffer RM, Bhatia K, Horii T, Bethony JM, Mbulaiteye SM, 2013. Endemic Burkitt lymphoma is associated with strength and diversity of Plasmodium falciparum malaria stage-specific antigen antibody response. Blood 122: 629–635.
-
6.
Piriou E, Kimmel R, Chelimo K, Middeldorp JM, Sumba P, Ploutz-snyder R, Moormann AM, Rochford R, 2009. Serological evidence for long-term Epstein–Barr virus reactivation in children living in a holoendemic malaria region of Kenya. J Med Virol 81: 1088–1093.
-
7.
Asito AS, Piriou E, Odada PS, Fiore N, Middeldorp JM, Long C, Dutta S, Lanar DE, Jura WG, Ouma C, Otieno JA, Moormann AM, Rochford R, 2010. Elevated anti-Zta IgG levels and EBV viral load are associated with site of tumor presentation in endemic Burkitt's lymphoma patients: a case control study. Infect Agent Cancer 5: 13.
-
8.
Johnston WT, Mutalima N, Sun D, Emmanuel B, Bhatia K, Aka P, Wu X, Borgstein E, Liomba GN, Kamiza S, Mkandawire N, Batumba M, Carpenter LM, Jaffe H, Molyneux EM, Goedert JJ, Soppet D, Newton R, Mbulaiteye SM, 2014. Relationship between Plasmodium falciparum malaria prevalence, genetic diversity and endemic Burkitt lymphoma in Malawi. Sci Rep 4: 3741.
-
9.
Bouvard V, Baan RA, Grosse Y, Lauby-Secretan B, El Ghissassi F, Benbrahim-Tallaa L, Guha N, Straif K; WHO International Agency for Research on Cancer Monograph Working Group, 2012. Carcinogenicity of malaria and of some polyomaviruses. Lancet Oncol 13: 339–340.
-
10.
Bhatt S, Weiss DJ, Cameron E, Bisanzio D, Mappin B, Dalrymple U, Battle KE, Moyes CL, Henry A, Eckhoff PA, Wenger EA, Briët O, Penny MA, Smith TA, Bennett A, Yukich J, Eisele TP, Griffin JT, Fergus CA, Lynch M, Lindgren F, Cohen JM, Murray CL, Smith DL, Hay SI, Cibulskis RE, Gething PW, 2015. The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015. Nature 526: 207–211.
-
11.
Ministerio da Saude (MISAU), Instituto Nacional de Estatística (INE), ICF International (ICFI), 2013. Moçambique Inquérito Demográfico E de Saúde 2011. Calverton, MD. Available at: http://dhsprogram.com/pubs/pdf/FR266/FR266.pdf. Accessed March 6, 2016.
-
12.
Carreira H, Lorenzoni C, Carrilho C, Ferro J, Sultane T, Garcia C, Amod F, Augusto O, Silva-Matos C, La Vecchia C, Lunet N, 2014. Spectrum of pediatric cancers in Mozambique: an analysis of hospital and population-based data. Pediatr Hematol Oncol 31: 498–508.
-
13.
Msyamboza KP, Dzamalala C, Mdokwe C, Kamiza S, Lemerani M, Dzowela T, Kathyola D, 2012. Burden of cancer in Malawi; common types, incidence and trends: national population-based cancer registry. BMC Res Notes 5: 149.
-
14.
Stefan DC, 2015. Patterns of distribution of childhood cancer in Africa. J Trop Pediatr 61: 165–173.
-
15.
Insituto Nacional de Estadística (Moçambique), 2007. Projeções anuais da população total, urbana e rural, 2007–2040. Available at: http://www.ine.gov.mz/estatisticas/estatisticas-demograficas-e-indicadores-sociais/populacao/projeccoes-da-populacao. Accessed October 8, 2015.
-
16.
Department of Zoology–University of Oxford, 2015. Malaria Atlas Project (MAP). Available at: http://www.map.ox.ac.uk/. Accessed May 2, 2016.
-
17.
Aka P, Kawira E, Masalu N, Emmanuel B, Brubaker G, Magatti J, Mbulaiteye SM, 2012. Incidence and trends in Burkitt lymphoma in northern Tanzania from 2000 to 2009. Pediatr Blood Cancer 59: 1234–1238.
-
18.
Rainey JJ, Omenah D, Sumba PO, Moormann AM, Rochford R, Wilson ML, 2007. Spatial clustering of endemic Burkitt's lymphoma in high-risk regions of Kenya. Int J Cancer 120: 121–127.
-
19.
Ogwang MD, Bhatia K, Biggar RJ, Mbulaiteye SM, 2008. Incidence and geographic distribution of endemic Burkitt lymphoma in northern Uganda revisited. Int J Cancer 123: 2658–2663.
-
20.
Sacarlal J, Nhacolo AQ, Sigaúque B, Nhalungo DA, Abacassamo F, Sacoor CN, Aide P, Machevo S, Nhampossa T, Macete EV, Bassat Q, David C, Bardají A, Letang E, Saúte F, Aponte JJ, Thompson R, Alonso PLA, 2009. 10 year study of the cause of death in children under 15 years in Manhiça, Mozambique. BMC Public Health 9: 67.
| Past two years | Past Year | Past 30 Days | |
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| Abstract Views | 161 | 110 | 14 |
| Full Text Views | 292 | 7 | 1 |
| PDF Downloads | 126 | 9 | 1 |
Incidence of Endemic Burkitt Lymphoma in Three Regions of Mozambique
Cristina O'Callaghan-Gordo
Cristina O'Callaghan-Gordo
ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
Universitat Pompeu Fabra (UPF), Barcelona, Spain.
CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
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Universitat Pompeu Fabra (UPF), Barcelona, Spain.
CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
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Delphine Casabonne
Delphine Casabonne
CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Unit of Infections and Cancer (UNIC), IDIBELL, Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.
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Unit of Infections and Cancer (UNIC), IDIBELL, Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.
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Carla Carrilho
Carla Carrilho
Serviço de Anatomia Patológica, Hospital Central do Maputo, Maputo, Mozambique.
Faculdade de Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique.
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Faculdade de Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique.
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Josefo Ferro
Josefo Ferro
Serviço de Anatomia Patológica, Hospital Central da Beira, Beira, Mozambique.
Universidade Católica de Moçambique, Beira, Mozambique.
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Universidade Católica de Moçambique, Beira, Mozambique.
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Cesaltina Lorenzoni
Cesaltina Lorenzoni
Serviço de Anatomia Patológica, Hospital Central do Maputo, Maputo, Mozambique.
Faculdade de Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique.
Programa Nacional de Controle do Cancro, Ministério da Saúde, Maputo, Mozambique.
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Faculdade de Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique.
Programa Nacional de Controle do Cancro, Ministério da Saúde, Maputo, Mozambique.
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Clesio Zaqueu
Clesio Zaqueu
Serviço de Anatomia Patológica, Hospital Central do Nampula, Nampula, Mozambique.
Faculdade de Ciências de Saúde, Universidade Lúrio, Nampula, Mozambique.
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Faculdade de Ciências de Saúde, Universidade Lúrio, Nampula, Mozambique.
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Augusto Nhabomba
Augusto Nhabomba
Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
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Ruth Aguilar
Ruth Aguilar
ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic–Universitat de Barcelona, Barcelona, Spain.
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Quique Bassat
Quique Bassat
Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic–Universitat de Barcelona, Barcelona, Spain.
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ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic–Universitat de Barcelona, Barcelona, Spain.
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Sílvia de Sanjosé
Sílvia de Sanjosé
CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Unit of Infections and Cancer (UNIC), IDIBELL, Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.
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Unit of Infections and Cancer (UNIC), IDIBELL, Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.
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Carlota Dobaño
Carlota Dobaño
Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic–Universitat de Barcelona, Barcelona, Spain.
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ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic–Universitat de Barcelona, Barcelona, Spain.
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Manolis Kogevinas
Manolis Kogevinas
ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
Universitat Pompeu Fabra (UPF), Barcelona, Spain.
CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Municipal Institute of Medical Research (IMIM-Hospital del Mar), Barcelona, Spain.
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Universitat Pompeu Fabra (UPF), Barcelona, Spain.
CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Municipal Institute of Medical Research (IMIM-Hospital del Mar), Barcelona, Spain.
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Abstract
Data on the burden and incidence of endemic Burkitt lymphoma (eBL) across Mozambique are scarce. We retrospectively retrieved information on eBL cases from reports of the three main hospitals of Mozambique: Maputo Central Hospital (MCH), Beira Central Hospital (BCH), and Nampula Central Hospital (NCH) between 2004 and 2014. For 2015, we prospectively collected information of new eBL cases attending these hospitals. A total of 512 eBL cases were reported between 2004 and 2015: 153 eBL cases were reported in MCH, 195 in BCH, and 164 in NCH. Mean age of cases was 6.9 years (standard deviation = 2.8); 63% (319/504) of cases were males. For 2015, the estimated incidence rate of eBL was 2.0, 1.7, and 3.9 per 106 person-year at risk in MCH, BCH, and NCH, respectively. Incidence was higher in NCH (northern Mozambique), where intensity of malaria transmission is higher. Data presented show that eBL is a common pediatric malignancy in Mozambique, as observed in neighboring countries.
Author Notes
Financial support: This project was funded by the CERCA Institutes Integration Program (SUMA 2013) (promoted and managed by the Secretariat for Universities and Research of the Ministry of Economy and Knowledge of the Government of Catalonia [SUR], the Agency for Management of University and Research Grants [AGAUR], and the CERCA Institute). Cristina O'Callaghan-Gordo holds a Sara Borrell postdoctoral fellowship awarded from the Carlos III National Institute of Health (CD13/00072). We thank Ibon Tamayo-Urria for mapping the cases of eBL.
Authors' addresses: Cristina O'Callaghan-Gordo and Manolis Kogevinas, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain, E-mails: cristina.ocallaghan@isglobal.org and manolis.kogevinas@isglobal.org. Delphine Casabonne and Sílvia de Sanjosé, Unit of Infections and Cancer (UNIC), IDIBELL, Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain, E-mails: dcasabonne@iconcologia.net and s.sanjose@iconcologia.net. Carla Carrilho and Cesaltina Lorenzoni, Serviço de Anatomia Patológica, Hospital Central do Maputo, Maputo, Mozambique, E-mails: carrilhocarla@hotmail.com and ferreira.cesaltina@gmail.com. Josefo Ferro, Department of Medicine, Catholic University of Mozambique, Beira, Mozambique, E-mail: josefoferro@yahoo.com.br. Clesio Zaqueu, Serviço de Anatomia Patológica, Hospital Central do Nampula, Nampula, Mozambique, E-mail: clesio.zaqueu@gmail.com. Augusto Nhabomba, Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique, E-mail: augusto.nhabomba@manhica.net. Ruth Aguilar, Quique Bassat, and Carlota Dobaño, ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic–Universitat de Barcelona, Barcelona, Spain, E-mails: ruth.aguilar@isglobal.org, quique.bassat@isglobal.org, and carlota.dobano@isglobal.org.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Molyneux EM, Rochford R, Griffin B, Newton R, Jackson G, Menon G, Harrison CJ, Israels T, Bailey S, 2012. Burkitt's lymphoma. Lancet 379: 1234–1244.
-
2.
Bouvard V, Baan R, Straif K, Grosse Y, Secretan B, El Ghissassi F, Benbrahim-Tallaa L, Guha N, Freeman C, Galichet L, Cogliano V, 2009. A review of human carcinogens: Part B: biological agents. Lancet Oncol 10: 321–322. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19350698. Accessed June 6, 2013.
-
3.
Carpenter LM, Newton R, Casabonne D, Ziegler J, Mbulaiteye S, Mbidde E, Wabinga H, Jaffe H, Beral V, 2008. Antibodies against malaria and Epstein-Barr virus in childhood Burkitt lymphoma: a case-control study in Uganda. Int J Cancer 122: 1319–1323.
-
4.
Mutalima N, Molyneux E, Jaffe H, Kamiza S, Borgstein E, Mkandawire N, Liomba G, Batumba M, Lagos D, Gratrix F, Boshoff C, Casabonne D, Carpenter LM, Newton R, 2008. Associations between Burkitt lymphoma among children in Malawi and infection with HIV, EBV and malaria: results from a case-control study. PLoS One 3: e2505.
-
5.
Aka P, Vila MC, Jariwala A, Nkrumah F, Emmanuel B, Yagi M, Palacpac NM, Periago MV, Neequaye J, Kiruthu C, Tougan T, Levine PH, Biggar RJ, Pfeiffer RM, Bhatia K, Horii T, Bethony JM, Mbulaiteye SM, 2013. Endemic Burkitt lymphoma is associated with strength and diversity of Plasmodium falciparum malaria stage-specific antigen antibody response. Blood 122: 629–635.
-
6.
Piriou E, Kimmel R, Chelimo K, Middeldorp JM, Sumba P, Ploutz-snyder R, Moormann AM, Rochford R, 2009. Serological evidence for long-term Epstein–Barr virus reactivation in children living in a holoendemic malaria region of Kenya. J Med Virol 81: 1088–1093.
-
7.
Asito AS, Piriou E, Odada PS, Fiore N, Middeldorp JM, Long C, Dutta S, Lanar DE, Jura WG, Ouma C, Otieno JA, Moormann AM, Rochford R, 2010. Elevated anti-Zta IgG levels and EBV viral load are associated with site of tumor presentation in endemic Burkitt's lymphoma patients: a case control study. Infect Agent Cancer 5: 13.
-
8.
Johnston WT, Mutalima N, Sun D, Emmanuel B, Bhatia K, Aka P, Wu X, Borgstein E, Liomba GN, Kamiza S, Mkandawire N, Batumba M, Carpenter LM, Jaffe H, Molyneux EM, Goedert JJ, Soppet D, Newton R, Mbulaiteye SM, 2014. Relationship between Plasmodium falciparum malaria prevalence, genetic diversity and endemic Burkitt lymphoma in Malawi. Sci Rep 4: 3741.
-
9.
Bouvard V, Baan RA, Grosse Y, Lauby-Secretan B, El Ghissassi F, Benbrahim-Tallaa L, Guha N, Straif K; WHO International Agency for Research on Cancer Monograph Working Group, 2012. Carcinogenicity of malaria and of some polyomaviruses. Lancet Oncol 13: 339–340.
-
10.
Bhatt S, Weiss DJ, Cameron E, Bisanzio D, Mappin B, Dalrymple U, Battle KE, Moyes CL, Henry A, Eckhoff PA, Wenger EA, Briët O, Penny MA, Smith TA, Bennett A, Yukich J, Eisele TP, Griffin JT, Fergus CA, Lynch M, Lindgren F, Cohen JM, Murray CL, Smith DL, Hay SI, Cibulskis RE, Gething PW, 2015. The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015. Nature 526: 207–211.
-
11.
Ministerio da Saude (MISAU), Instituto Nacional de Estatística (INE), ICF International (ICFI), 2013. Moçambique Inquérito Demográfico E de Saúde 2011. Calverton, MD. Available at: http://dhsprogram.com/pubs/pdf/FR266/FR266.pdf. Accessed March 6, 2016.
-
12.
Carreira H, Lorenzoni C, Carrilho C, Ferro J, Sultane T, Garcia C, Amod F, Augusto O, Silva-Matos C, La Vecchia C, Lunet N, 2014. Spectrum of pediatric cancers in Mozambique: an analysis of hospital and population-based data. Pediatr Hematol Oncol 31: 498–508.
-
13.
Msyamboza KP, Dzamalala C, Mdokwe C, Kamiza S, Lemerani M, Dzowela T, Kathyola D, 2012. Burden of cancer in Malawi; common types, incidence and trends: national population-based cancer registry. BMC Res Notes 5: 149.
-
14.
Stefan DC, 2015. Patterns of distribution of childhood cancer in Africa. J Trop Pediatr 61: 165–173.
-
15.
Insituto Nacional de Estadística (Moçambique), 2007. Projeções anuais da população total, urbana e rural, 2007–2040. Available at: http://www.ine.gov.mz/estatisticas/estatisticas-demograficas-e-indicadores-sociais/populacao/projeccoes-da-populacao. Accessed October 8, 2015.
-
16.
Department of Zoology–University of Oxford, 2015. Malaria Atlas Project (MAP). Available at: http://www.map.ox.ac.uk/. Accessed May 2, 2016.
-
17.
Aka P, Kawira E, Masalu N, Emmanuel B, Brubaker G, Magatti J, Mbulaiteye SM, 2012. Incidence and trends in Burkitt lymphoma in northern Tanzania from 2000 to 2009. Pediatr Blood Cancer 59: 1234–1238.
-
18.
Rainey JJ, Omenah D, Sumba PO, Moormann AM, Rochford R, Wilson ML, 2007. Spatial clustering of endemic Burkitt's lymphoma in high-risk regions of Kenya. Int J Cancer 120: 121–127.
-
19.
Ogwang MD, Bhatia K, Biggar RJ, Mbulaiteye SM, 2008. Incidence and geographic distribution of endemic Burkitt lymphoma in northern Uganda revisited. Int J Cancer 123: 2658–2663.
-
20.
Sacarlal J, Nhacolo AQ, Sigaúque B, Nhalungo DA, Abacassamo F, Sacoor CN, Aide P, Machevo S, Nhampossa T, Macete EV, Bassat Q, David C, Bardají A, Letang E, Saúte F, Aponte JJ, Thompson R, Alonso PLA, 2009. 10 year study of the cause of death in children under 15 years in Manhiça, Mozambique. BMC Public Health 9: 67.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 161 | 110 | 14 |
| Full Text Views | 292 | 7 | 1 |
| PDF Downloads | 126 | 9 | 1 |