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RefWorks
Reference Manager
BibTeX
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-
1
National Center for Health Development, Ministry of Health of Mongolia, 2008. Health Indicators 2007. Ulaanbaatar: Ministry of Health.
-
2
Jacobson KH, Koopman JS, 2004. Declining hepatitis A seroprevalence: a global review and analysis. Epidemiol Infect 132 :1005–1022.
-
3
World Health Organization, 2000. Hepatitis A vaccines. Wkly Epidemiol Rec 75 :38–44.
-
4
Braunwald E, Fauci AS, Iaspar DL, Hauser SL, Longo DL, Jameson JL, 2001. Harrison’s Principles of Internal Medicine. Fifteenth edition, 1694–1710.
-
5
Takahashi M, Nishizawa T, Gotanda Y, Tsuda F, Komatsu F, Kawabata T, Hasegawa K, Altankhuu M, Chimedregzen U, Narantuya L, Hoshino H, Hino K, Kagawa Y, Okamoto H, 2004. High prevalence of antibodies to hepatitis A and E viruses and viremia of hepatitis B, C, and D viruses among apparently healthy populations in Mongolia. Clin Diagn Lab Immunol 11 :392–398.
-
6
Tsatsralt-Od B, Takahashi M, Endo K, Agiimaa D, Buyankhuu O, Okamoto H, 2007. Comparison of hepatitis A and E virus infections among healthy children in Mongolia: evidence for infection with a subgenotype IA HAV in children, 2007. J Med Virol 79 :18–25.
-
7
Davaalkham D, Ojima T, Uehara R, Watanabe M, Oki I, Wiersma S, Nymadawa P, Nakamura Y, 2007. Impact of the Universal Hepatitis B Immunization Program in Mongolia: achievements and challenges. J Epidemiol 17 :69–75.
-
8
Davaalkham D, Ojima T, Uehara R, Watanabe M, Oki I, Nymadawa P, Takahashi M, Okamoto H, Nakamura Y, 2006. Hepatitis delta virus infection in Mongolia: analyses of geographic distribution, risk factors and disease severity. Am J Trop Med Hyg 75 :365–369.
-
9
Mitsui T, Tsukamoto Y, Hirose A, Suzuki S, Yamazaki C, Masuko K, Tsuda F, Endo K, Takahashi M, Okamoto H, 2006. Distinct changing profiles of hepatitis A and E virus infection among patients with acute hepatitis, patients on maintenance hemodialysis and healthy individuals in Japan. J Med Virol 78 :1015–1024.
-
10
Takahashi M, Kusakai S, Mizuo H, Suzuki K, Fujimura K, Masuko K, Sugai Y, Aikawa T, Nishizawa T, Okamoto H, 2005. Simultaneous detection of immunoglobulin A (IgA) and IgM anibodies against hepatitis E virus (HEV) is highly specific for diagnosis of acute HEV infection. J Clin Microbiol 43 :49–56.
-
11
Mizuo H, Suzuki K, Takikawa Y, Sugai Y, Tokita H, Akahane Y, Itoh K, Gotanda Y, Takahashi M, Nishizawa T, Okamoto H, 2002. Polyphyletic strains of hepatitis E virus are responsible for sporadic cases of acute hepatitis in Japan. J Clin Microbiol 40 :3209–3218.
-
12
Arankalle VA, Joshi MV, Kulkarni AM, Gandhe SS, Chobe LP, Rautmare SS, Mishra AC, Padbidri VS, 2001. Prevalence of anti-hepatitis E virus antibodies in different Indian animal species. J Viral Hepat 8 :223–227.
-
13
Purcell RH, Emerson SU, 2001. Animal models of hepatitis A and E. ILAR J 42 :161–177.
-
14
Letaief A, Kaabia N, Gaha R, Bousaadia A, Lazrag F, Trabelsi H, Ghannem H, Jemni L, 2005. Age-specific seroprevalence of hepatitis A among school children in central Tunisia. Am J Trop Med Hyg 73 :40–43.
-
15
Jacobsen KH, Koopman JS, 2005. The effects of socioeconomic development on worldwide hepatitis a virus seroprevalence patterns. Int J Epidemiol 34 :600–609.
-
16
Omana VN, Guoliang X, Gilberto V, Harold SM, 2006. Diagnosis of hepatitis A virus infection: a molecular approach. Clin Microbiol Rev 19 :63–79.
-
17
Endo K, Inoue J, Takahashi M, Mitsui T, Masuko K, Akahane Y, Okamoto H, 2007. Analysis of the full-length genome of a sub-genotype IIIB hepatitis A virus isolate: primers for broadly reactive PCR and genotypic analysis. J Med Virol 79 :8–17.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 143 | 119 | 7 |
| Full Text Views | 234 | 2 | 0 |
| PDF Downloads | 54 | 2 | 0 |
Hepatitis A and E Virus Infections among Children in Mongolia
Dambadarjaa Davaalkham
Dambadarjaa Davaalkham
Department of Epidemiology and Biostatistics, School of Public Health, Health Sciences University of Mongolia, Ulaanbaatar, Mongolia; Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Tochigi-Ken, Japan; Department of Public Health, Jichi Medical University School of Medicine, Tochigi-Ken, Japan
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Tsogzolbaatar Enkhoyun
Tsogzolbaatar Enkhoyun
Department of Epidemiology and Biostatistics, School of Public Health, Health Sciences University of Mongolia, Ulaanbaatar, Mongolia; Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Tochigi-Ken, Japan; Department of Public Health, Jichi Medical University School of Medicine, Tochigi-Ken, Japan
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Masaharu Takahashi
Masaharu Takahashi
Department of Epidemiology and Biostatistics, School of Public Health, Health Sciences University of Mongolia, Ulaanbaatar, Mongolia; Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Tochigi-Ken, Japan; Department of Public Health, Jichi Medical University School of Medicine, Tochigi-Ken, Japan
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Yosikazu Nakamura
Yosikazu Nakamura
Department of Epidemiology and Biostatistics, School of Public Health, Health Sciences University of Mongolia, Ulaanbaatar, Mongolia; Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Tochigi-Ken, Japan; Department of Public Health, Jichi Medical University School of Medicine, Tochigi-Ken, Japan
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Hiroaki Okamoto
Hiroaki Okamoto
Department of Epidemiology and Biostatistics, School of Public Health, Health Sciences University of Mongolia, Ulaanbaatar, Mongolia; Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Tochigi-Ken, Japan; Department of Public Health, Jichi Medical University School of Medicine, Tochigi-Ken, Japan
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To compare the epidemiologic profiles of hepatitis A virus (HAV) and hepatitis E virus (HEV) infections in children in Mongolia, the prevalence of HAV and HEV infections was studied serologically and molecularly among 520 apparently healthy children 7–12 years of age (mean ± standard deviation, 8.5 ± 0.8 years) using serum samples obtained in 2004. Total antibody against HAV (anti-HAV) was detected in 438 children (84.2%), whereas IgG antibody against HEV (anti-HEV IgG) was detected in only three subjects (0.6%). All three subjects with anti-HEV IgG were negative for anti-HEV IgM and HEV RNA. The presence of HAV RNA was tested in all 520 subjects, and one child (9-year-old girl) was found to have detectable HAV RNA (subgenotype IA). In conclusion, HEV infection was uncommon, but subclinical HAV infection was highly prevalent among children in Mongolia.
Author Notes
ProCite
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Reference Manager
BibTeX
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-
1
National Center for Health Development, Ministry of Health of Mongolia, 2008. Health Indicators 2007. Ulaanbaatar: Ministry of Health.
-
2
Jacobson KH, Koopman JS, 2004. Declining hepatitis A seroprevalence: a global review and analysis. Epidemiol Infect 132 :1005–1022.
-
3
World Health Organization, 2000. Hepatitis A vaccines. Wkly Epidemiol Rec 75 :38–44.
-
4
Braunwald E, Fauci AS, Iaspar DL, Hauser SL, Longo DL, Jameson JL, 2001. Harrison’s Principles of Internal Medicine. Fifteenth edition, 1694–1710.
-
5
Takahashi M, Nishizawa T, Gotanda Y, Tsuda F, Komatsu F, Kawabata T, Hasegawa K, Altankhuu M, Chimedregzen U, Narantuya L, Hoshino H, Hino K, Kagawa Y, Okamoto H, 2004. High prevalence of antibodies to hepatitis A and E viruses and viremia of hepatitis B, C, and D viruses among apparently healthy populations in Mongolia. Clin Diagn Lab Immunol 11 :392–398.
-
6
Tsatsralt-Od B, Takahashi M, Endo K, Agiimaa D, Buyankhuu O, Okamoto H, 2007. Comparison of hepatitis A and E virus infections among healthy children in Mongolia: evidence for infection with a subgenotype IA HAV in children, 2007. J Med Virol 79 :18–25.
-
7
Davaalkham D, Ojima T, Uehara R, Watanabe M, Oki I, Wiersma S, Nymadawa P, Nakamura Y, 2007. Impact of the Universal Hepatitis B Immunization Program in Mongolia: achievements and challenges. J Epidemiol 17 :69–75.
-
8
Davaalkham D, Ojima T, Uehara R, Watanabe M, Oki I, Nymadawa P, Takahashi M, Okamoto H, Nakamura Y, 2006. Hepatitis delta virus infection in Mongolia: analyses of geographic distribution, risk factors and disease severity. Am J Trop Med Hyg 75 :365–369.
-
9
Mitsui T, Tsukamoto Y, Hirose A, Suzuki S, Yamazaki C, Masuko K, Tsuda F, Endo K, Takahashi M, Okamoto H, 2006. Distinct changing profiles of hepatitis A and E virus infection among patients with acute hepatitis, patients on maintenance hemodialysis and healthy individuals in Japan. J Med Virol 78 :1015–1024.
-
10
Takahashi M, Kusakai S, Mizuo H, Suzuki K, Fujimura K, Masuko K, Sugai Y, Aikawa T, Nishizawa T, Okamoto H, 2005. Simultaneous detection of immunoglobulin A (IgA) and IgM anibodies against hepatitis E virus (HEV) is highly specific for diagnosis of acute HEV infection. J Clin Microbiol 43 :49–56.
-
11
Mizuo H, Suzuki K, Takikawa Y, Sugai Y, Tokita H, Akahane Y, Itoh K, Gotanda Y, Takahashi M, Nishizawa T, Okamoto H, 2002. Polyphyletic strains of hepatitis E virus are responsible for sporadic cases of acute hepatitis in Japan. J Clin Microbiol 40 :3209–3218.
-
12
Arankalle VA, Joshi MV, Kulkarni AM, Gandhe SS, Chobe LP, Rautmare SS, Mishra AC, Padbidri VS, 2001. Prevalence of anti-hepatitis E virus antibodies in different Indian animal species. J Viral Hepat 8 :223–227.
-
13
Purcell RH, Emerson SU, 2001. Animal models of hepatitis A and E. ILAR J 42 :161–177.
-
14
Letaief A, Kaabia N, Gaha R, Bousaadia A, Lazrag F, Trabelsi H, Ghannem H, Jemni L, 2005. Age-specific seroprevalence of hepatitis A among school children in central Tunisia. Am J Trop Med Hyg 73 :40–43.
-
15
Jacobsen KH, Koopman JS, 2005. The effects of socioeconomic development on worldwide hepatitis a virus seroprevalence patterns. Int J Epidemiol 34 :600–609.
-
16
Omana VN, Guoliang X, Gilberto V, Harold SM, 2006. Diagnosis of hepatitis A virus infection: a molecular approach. Clin Microbiol Rev 19 :63–79.
-
17
Endo K, Inoue J, Takahashi M, Mitsui T, Masuko K, Akahane Y, Okamoto H, 2007. Analysis of the full-length genome of a sub-genotype IIIB hepatitis A virus isolate: primers for broadly reactive PCR and genotypic analysis. J Med Virol 79 :8–17.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 143 | 119 | 7 |
| Full Text Views | 234 | 2 | 0 |
| PDF Downloads | 54 | 2 | 0 |