Tick Transmission of Babesia Microti to Rhesus Monkeys (Macaca Mulatta)

Trenton K. Ruebush II Vector Biology and Control Division, Bureau of Tropical Diseases, Centers for Disease Control, Public Health Service, U. S. Department of Health and Human Services, Department of Tropical Public Health, Harvard University School of Public Health, Atlanta Georgia 30333

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Joseph Piesman Vector Biology and Control Division, Bureau of Tropical Diseases, Centers for Disease Control, Public Health Service, U. S. Department of Health and Human Services, Department of Tropical Public Health, Harvard University School of Public Health, Atlanta Georgia 30333

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William E. Collins Vector Biology and Control Division, Bureau of Tropical Diseases, Centers for Disease Control, Public Health Service, U. S. Department of Health and Human Services, Department of Tropical Public Health, Harvard University School of Public Health, Atlanta Georgia 30333

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Andrew Spielman Vector Biology and Control Division, Bureau of Tropical Diseases, Centers for Disease Control, Public Health Service, U. S. Department of Health and Human Services, Department of Tropical Public Health, Harvard University School of Public Health, Atlanta Georgia 30333

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McWilson Warren Vector Biology and Control Division, Bureau of Tropical Diseases, Centers for Disease Control, Public Health Service, U. S. Department of Health and Human Services, Department of Tropical Public Health, Harvard University School of Public Health, Atlanta Georgia 30333

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To determine whether Ixodes dammini is capable of transmitting Babesia microti to primates, infected nymphal ticks were allowed to feed on five Macaca mulatta. The monkeys were then followed for at least 60 days with daily thick blood smears for evidence of infection. Patent B. microti parasitemia developed in four of the five animals. Prepatent periods were 13, 18, 20, and 28 days. Maximum parasitemia ranged from 83 to 7,068 organisms/mm3 blood. Splenectomy 15–17 months after exposure to ticks resulted in recurrences of parasitemia in three of the four infected monkeys.

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