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Reference Manager
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-
1.
Arum SO, Weldon CW, Orindi B, Landmann T, Tchouassi DP, Affognon HD, Sang R, 2015. Distribution and diversity of the vectors of Rift Valley fever along the livestock movement routes in the northeastern and coastal regions of Kenya. Parasit Vectors 8: 294.
-
2.
LaBeaud AD, Muchiri EM, Ndzovu M, Mwanje MT, Muiruri S, Peters CJ, King CH, 2008. Interepidemic Rift Valley fever virus seropositivity, northeastern Kenya. Emerg Infect Dis 14: 1240–1246.
-
3.
LaBeaud AD, Muiruri S, Sutherland LJ, Dahir S, Gildengorin G, Morrill J, Muchiri EM, Peters CJ, King CH, 2011. Postepidemic analysis of Rift Valley fever virus transmission in northeastern Kenya: a village cohort study. PLoS Negl Trop Dis 5: e1265.
-
4.
LaBeaud AD, Ochiai Y, Peters CJ, Muchiri EM, King CH, 2007. Spectrum of Rift Valley fever virus transmission in Kenya: insights from three distinct regions. Am J Trop Med Hyg 76: 795–800.
-
5.
LaBeaud AD, Pfeil S, Muiruri S, Dahir S, Sutherland LJ, Traylor Z, Gildengorin G, Muchiri EM, Morrill J, Peters CJ, Hise AG, Kazura JW, King CH, 2015. Factors associated with severe human Rift Valley fever in Sangailu, Garissa County, Kenya. PLoS Negl Trop Dis 9: e0003548.
-
6.
Linthicum KJ, Britch SC, Anyamba A, 2016. Rift Valley fever: an emerging mosquito-borne disease. Annu Rev Entomol 61: 395–415.
-
7.
Tchouassi DP, Bastos AD, Sole CL, Diallo M, Lutomiah J, Mutisya J, Mulwa F, Borgemeister C, Sang R, Torto B, 2014. Population genetics of two key mosquito vectors of Rift Valley fever virus reveals new insights into the changing disease outbreak patterns in Kenya. PLoS Negl Trop Dis 8: e3364.
-
8.
Kahlon SS, Peters CJ, Leduc J, Muchiri EM, Muiruri S, Njenga MK, Breiman RF, White AC Jr, King CH, 2010. Severe Rift Valley fever may present with a characteristic clinical syndrome. Am J Trop Med Hyg 82: 371–375.
-
9.
Munyua P, Murithi RM, Wainwright S, Githinji J, Hightower A, Mutonga D, Macharia J, Ithondeka PM, Musaa J, Breiman RF, Bloland P, Njenga MK, 2010. Rift Valley fever outbreak in livestock in Kenya, 2006–2007. Am J Trop Med Hyg 83: 58–64.
-
10.
Muga GO, Onyango-Ouma W, Sang R, Affognon H, 2015. Sociocultural and economic dimensions of Rift Valley fever. Am J Trop Med Hyg 92: 730–738.
-
11.
Jost CCNS, Kihu S, Bett B, Njogu G, Swai ES, Mariner JC, 2010. Epidemiological assessment of the Rift Valley fever outbreak in Kenya and Tanzania in 2006 and 2007. Am J Trop Med Hyg 83: 65–72.
-
12.
Ng’ang’a CMBS, Bett BK, 2016. Lay perceptions of risk factors for Rift Valley fever in a pastoral community in northeastern Kenya. BMC Public Health 16: 32.
-
13.
Owange NOOW, Kasiiti J, Gathura PB, Okuthe S, Sang R, Affognon H, Onyango-Ouma W, Landmann TT, Mbabu M, 2014. Perceived risk factors and risk pathways of Rift Valley fever in cattle in Ijaea district, Kenya. Onderstepoort J Vet Res 81.
-
14.
Bisanzio D, Mutuku F, Bustinduy AL, Mungai PL, Muchiri EM, King CH, Kitron U, 2014. Cross-sectional study of the burden of vector-borne and soil-transmitted polyparasitism in rural communities of Coast Province, Kenya. PLoS Negl Trop Dis 8: e2992.
-
15.
Mbogo CM, Mwangangi JM, Nzovu J, Gu W, Yan G, Gunter JT, Swalm C, Keating J, Regens JL, Shililu JI, Githure JI, Beier JC, 2003. Spatial and temporal heterogeneity of Anopheles mosquitoes and Plasmodium falciparum transmission along the Kenyan coast. Am J Trop Med Hyg 68: 734–742.
-
16.
Mutuku FM, King CH, Mungai P, Mbogo C, Mwangangi J, Muchiri EM, Walker ED, Kitron U, 2011. Impact of insecticide-treated bed nets on malaria transmission indices on the south coast of Kenya. Malar J 10: 356.
-
17.
Gwatkin DRRS, Johnson K, Suliman E, Wagstaff A, Amouzou A, 2007. Socio-economic differences in health, nutrition, and population: Kenya 1993, 1998, 2003. Country reports on HNP and poverty. Washington, DC. World Bank Group 1: 1–150.
-
18.
Muiruri S, Kabiru EW, Muchiri EM, Hussein H, Kagondu F, LaBeaud AD, King CH, 2015. Cross-sectional survey of Rift Valley fever virus exposure in Bodhei village located in a transitional coastal forest habitat in Lamu county, Kenya. Am J Trop Med Hyg 92: 394–400.
-
19.
Mohamed M, Mosha F, Mghamba J, Zaki SR, Shieh WJ, Paweska J, Omulo S, Gikundi S, Mmbuji P, Bloland P, Zeidner N, Kalinga R, Breiman RF, Njenga MK, 2010. Epidemiologic and clinical aspects of a Rift Valley fever outbreak in humans in Tanzania, 2007. Am J Trop Med Hyg 83: 22–27.
-
20.
Murithi RM, Munyua P, Ithondeka PM, Macharia JM, Hightower A, Luman ET, Breiman RF, Njenga MK, 2011. Rift Valley fever in Kenya: history of epizootics and identification of vulnerable districts. Epidemiol Infect 139: 372–380.
-
21.
Aagaard-Hansen JNN, Alvar J, 2010. Population movement: a key factor in the epidemiology of neglected tropical diseases. Trop Med Int Health 15: 1281–1288.
-
22.
Gray GC, Anderson BD, LaBeaud AD, Heraud JM, Fevre EM, Andriamandimby SF, Cook EA, Dahir S, de Glanville WA, Heil GL, Khan SU, Muiruri S, Olive MM, Thomas LF, Merrill HR, Merrill ML, Richt JA, 2015. Seroepidemiological study of interepidemic Rift Valley fever virus Infection among persons with intense ruminant exposure in Madagascar and Kenya. Am J Trop Med Hyg 93: 1364–1370.
-
23.
WHO, 1998. Proceedings of the International Conference on Emerging Infectious Diseases. Atlanta, Georgia, USA March 8–11, 1998. Emerg Infect Dis 4: 353–505.
-
24.
Anyamba A, Chretien JP, Small J, Tucker CJ, Formenty PB, Richardson JH, Britch SC, Schnabel DC, Erickson RL, Linthicum KJ, 2009. Prediction of a Rift Valley fever outbreak. Proc Natl Acad Sci USA 106: 955–959.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 667 | 553 | 46 |
| Full Text Views | 536 | 25 | 0 |
| PDF Downloads | 202 | 20 | 0 |
Rift Valley Fever Seroprevalence in Coastal Kenya
Elysse N. Grossi-Soyster
Elysse N. Grossi-Soyster
Stanford University School of Medicine, Stanford, California
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Tamara Banda
Tamara Banda
Children’s Hospital Oakland Research Institute, Oakland, California
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Crystal Y. Teng
Crystal Y. Teng
Children’s Hospital Oakland Research Institute, Oakland, California
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Eric M. Muchiri
Eric M. Muchiri
Division of Vector Borne and Neglected Tropical Diseases, Ministry of Health, Msambweni, Kenya
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Peter L. Mungai
Peter L. Mungai
Division of Vector Borne and Neglected Tropical Diseases, Ministry of Health, Msambweni, Kenya
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Francis M. Mutuku
Francis M. Mutuku
Division of Vector Borne and Neglected Tropical Diseases, Ministry of Health, Msambweni, Kenya
Department of Environmental studies, Emory University, Atlanta, Georgia
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Department of Environmental studies, Emory University, Atlanta, Georgia
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Ginny Gildengorin
Ginny Gildengorin
Children’s Hospital Oakland Research Institute, Oakland, California
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Uriel Kitron
Uriel Kitron
Department of Environmental studies, Emory University, Atlanta, Georgia
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Charles H. King
Charles H. King
Case Western Reserve University, Cleveland, Ohio
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A. Desiree Labeaud
A. Desiree Labeaud
Stanford University School of Medicine, Stanford, California
Children’s Hospital Oakland Research Institute, Oakland, California
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Children’s Hospital Oakland Research Institute, Oakland, California
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Rift Valley fever virus (RVFV) causes severe disease in both animals and humans, resulting in significant economic and public health damages. The objective of this study was to measure RVFV seroprevalence in six coastal Kenyan villages between 2009 and 2011, and characterize individual-, household-, and community-level risk factors for prior RVFV exposure. Sera were tested for anti-RVFV IgG via enzyme-linked immunosorbent assay. Overall, 51 (1.8%; confidence interval [CI95] 1.3–2.3) of 2,871 samples were seropositive for RVFV. Seroprevalence differed significantly among villages, and was highest in Jego Village (18/300; 6.0%; CI95 3.6–9.3) and lowest in Magodzoni (0/248). Adults were more likely to be seropositive than children (P < 0.001). Seropositive subjects were less likely to own land or a motor vehicle (P < 0.01), suggesting exposure is associated with lower socioeconomic standing (P = 0.03). RVFV exposure appears to be low in coastal Kenya, although with some variability among villages.
Author Notes
Financial support: The Pacific North Western Regional Center of Excellence AI81680: Research Project 012 (ADL), NIH/EEID TW008067 (UK and CHK), and the National Institutes of Health (NIH) (R01AI102918, LaBeaud).
Authors’ addresses: Elysse N. Grossi-Soyster and A. Desiree Labeaud, Pediatrics Infectious Disease Division, Stanford University School of Medicine, Stanford, CA, E-mails: elysse@stanford.edu and dlabeaud@stanford.edu. Tamara Banda, Aduro Biotech, CA, E-mail: tbanda@aduro.com. Crystal Y. Teng, University of Southern California School of Pharmacy, Los Angeles, CA, E-mail: cteng6@gmail.com. Eric M. Muchiri, Division of Vector Borne and Neglected Tropical Diseases, Ministry of Health, Msambweni, Kenya, E-mail: ericmuchiri@gmail.com. Francis M. Mutuku, Department of Environmental Health and Sciences, Technical University of Mombasa, Mombasa, Kenya, E-mail: fmutuku73@gmail.com. Ginny Gildengorin, Children’s Hospital of Oakland Research Institute, Oakland, CA, E-mail: ggildengorin@mail.cho.org. Uriel Kitron, Department of Environmental Sciences, Emory University, Atlanta, GA, E-mail: ukitron@emory.edu. Charles H. King, Center for Global Health and Disease, Case Western Reserve University, Cleveland, OH, E-mail: chk@case.edu.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Arum SO, Weldon CW, Orindi B, Landmann T, Tchouassi DP, Affognon HD, Sang R, 2015. Distribution and diversity of the vectors of Rift Valley fever along the livestock movement routes in the northeastern and coastal regions of Kenya. Parasit Vectors 8: 294.
-
2.
LaBeaud AD, Muchiri EM, Ndzovu M, Mwanje MT, Muiruri S, Peters CJ, King CH, 2008. Interepidemic Rift Valley fever virus seropositivity, northeastern Kenya. Emerg Infect Dis 14: 1240–1246.
-
3.
LaBeaud AD, Muiruri S, Sutherland LJ, Dahir S, Gildengorin G, Morrill J, Muchiri EM, Peters CJ, King CH, 2011. Postepidemic analysis of Rift Valley fever virus transmission in northeastern Kenya: a village cohort study. PLoS Negl Trop Dis 5: e1265.
-
4.
LaBeaud AD, Ochiai Y, Peters CJ, Muchiri EM, King CH, 2007. Spectrum of Rift Valley fever virus transmission in Kenya: insights from three distinct regions. Am J Trop Med Hyg 76: 795–800.
-
5.
LaBeaud AD, Pfeil S, Muiruri S, Dahir S, Sutherland LJ, Traylor Z, Gildengorin G, Muchiri EM, Morrill J, Peters CJ, Hise AG, Kazura JW, King CH, 2015. Factors associated with severe human Rift Valley fever in Sangailu, Garissa County, Kenya. PLoS Negl Trop Dis 9: e0003548.
-
6.
Linthicum KJ, Britch SC, Anyamba A, 2016. Rift Valley fever: an emerging mosquito-borne disease. Annu Rev Entomol 61: 395–415.
-
7.
Tchouassi DP, Bastos AD, Sole CL, Diallo M, Lutomiah J, Mutisya J, Mulwa F, Borgemeister C, Sang R, Torto B, 2014. Population genetics of two key mosquito vectors of Rift Valley fever virus reveals new insights into the changing disease outbreak patterns in Kenya. PLoS Negl Trop Dis 8: e3364.
-
8.
Kahlon SS, Peters CJ, Leduc J, Muchiri EM, Muiruri S, Njenga MK, Breiman RF, White AC Jr, King CH, 2010. Severe Rift Valley fever may present with a characteristic clinical syndrome. Am J Trop Med Hyg 82: 371–375.
-
9.
Munyua P, Murithi RM, Wainwright S, Githinji J, Hightower A, Mutonga D, Macharia J, Ithondeka PM, Musaa J, Breiman RF, Bloland P, Njenga MK, 2010. Rift Valley fever outbreak in livestock in Kenya, 2006–2007. Am J Trop Med Hyg 83: 58–64.
-
10.
Muga GO, Onyango-Ouma W, Sang R, Affognon H, 2015. Sociocultural and economic dimensions of Rift Valley fever. Am J Trop Med Hyg 92: 730–738.
-
11.
Jost CCNS, Kihu S, Bett B, Njogu G, Swai ES, Mariner JC, 2010. Epidemiological assessment of the Rift Valley fever outbreak in Kenya and Tanzania in 2006 and 2007. Am J Trop Med Hyg 83: 65–72.
-
12.
Ng’ang’a CMBS, Bett BK, 2016. Lay perceptions of risk factors for Rift Valley fever in a pastoral community in northeastern Kenya. BMC Public Health 16: 32.
-
13.
Owange NOOW, Kasiiti J, Gathura PB, Okuthe S, Sang R, Affognon H, Onyango-Ouma W, Landmann TT, Mbabu M, 2014. Perceived risk factors and risk pathways of Rift Valley fever in cattle in Ijaea district, Kenya. Onderstepoort J Vet Res 81.
-
14.
Bisanzio D, Mutuku F, Bustinduy AL, Mungai PL, Muchiri EM, King CH, Kitron U, 2014. Cross-sectional study of the burden of vector-borne and soil-transmitted polyparasitism in rural communities of Coast Province, Kenya. PLoS Negl Trop Dis 8: e2992.
-
15.
Mbogo CM, Mwangangi JM, Nzovu J, Gu W, Yan G, Gunter JT, Swalm C, Keating J, Regens JL, Shililu JI, Githure JI, Beier JC, 2003. Spatial and temporal heterogeneity of Anopheles mosquitoes and Plasmodium falciparum transmission along the Kenyan coast. Am J Trop Med Hyg 68: 734–742.
-
16.
Mutuku FM, King CH, Mungai P, Mbogo C, Mwangangi J, Muchiri EM, Walker ED, Kitron U, 2011. Impact of insecticide-treated bed nets on malaria transmission indices on the south coast of Kenya. Malar J 10: 356.
-
17.
Gwatkin DRRS, Johnson K, Suliman E, Wagstaff A, Amouzou A, 2007. Socio-economic differences in health, nutrition, and population: Kenya 1993, 1998, 2003. Country reports on HNP and poverty. Washington, DC. World Bank Group 1: 1–150.
-
18.
Muiruri S, Kabiru EW, Muchiri EM, Hussein H, Kagondu F, LaBeaud AD, King CH, 2015. Cross-sectional survey of Rift Valley fever virus exposure in Bodhei village located in a transitional coastal forest habitat in Lamu county, Kenya. Am J Trop Med Hyg 92: 394–400.
-
19.
Mohamed M, Mosha F, Mghamba J, Zaki SR, Shieh WJ, Paweska J, Omulo S, Gikundi S, Mmbuji P, Bloland P, Zeidner N, Kalinga R, Breiman RF, Njenga MK, 2010. Epidemiologic and clinical aspects of a Rift Valley fever outbreak in humans in Tanzania, 2007. Am J Trop Med Hyg 83: 22–27.
-
20.
Murithi RM, Munyua P, Ithondeka PM, Macharia JM, Hightower A, Luman ET, Breiman RF, Njenga MK, 2011. Rift Valley fever in Kenya: history of epizootics and identification of vulnerable districts. Epidemiol Infect 139: 372–380.
-
21.
Aagaard-Hansen JNN, Alvar J, 2010. Population movement: a key factor in the epidemiology of neglected tropical diseases. Trop Med Int Health 15: 1281–1288.
-
22.
Gray GC, Anderson BD, LaBeaud AD, Heraud JM, Fevre EM, Andriamandimby SF, Cook EA, Dahir S, de Glanville WA, Heil GL, Khan SU, Muiruri S, Olive MM, Thomas LF, Merrill HR, Merrill ML, Richt JA, 2015. Seroepidemiological study of interepidemic Rift Valley fever virus Infection among persons with intense ruminant exposure in Madagascar and Kenya. Am J Trop Med Hyg 93: 1364–1370.
-
23.
WHO, 1998. Proceedings of the International Conference on Emerging Infectious Diseases. Atlanta, Georgia, USA March 8–11, 1998. Emerg Infect Dis 4: 353–505.
-
24.
Anyamba A, Chretien JP, Small J, Tucker CJ, Formenty PB, Richardson JH, Britch SC, Schnabel DC, Erickson RL, Linthicum KJ, 2009. Prediction of a Rift Valley fever outbreak. Proc Natl Acad Sci USA 106: 955–959.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 667 | 553 | 46 |
| Full Text Views | 536 | 25 | 0 |
| PDF Downloads | 202 | 20 | 0 |