Lack of Evidence of Hepatitis C and HIV Co-Infection among Men Who Have Sex with Men in Peru

Javier R. Lama Investigaciones Medicas en Salud (INMENSA), Lima, Peru; National Institute of Health, and General Directorate of Epidemiology, Ministry of Health of Peru, Lima, Peru

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Aldo Lucchetti Investigaciones Medicas en Salud (INMENSA), Lima, Peru; National Institute of Health, and General Directorate of Epidemiology, Ministry of Health of Peru, Lima, Peru

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Cesar Cabezas Investigaciones Medicas en Salud (INMENSA), Lima, Peru; National Institute of Health, and General Directorate of Epidemiology, Ministry of Health of Peru, Lima, Peru

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Luis Suarez-Ognio Investigaciones Medicas en Salud (INMENSA), Lima, Peru; National Institute of Health, and General Directorate of Epidemiology, Ministry of Health of Peru, Lima, Peru

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Hepatitis C virus (HCV) infection occurs among human immunodeficiency virus (HIV)-infected men who have sex with men (MSM) because of shared routes of transmission. To assess the association between HCV and HIV infection among MSM in Peru, we conducted a matched case-control study (162 HIV-positive cases and 324 HIV-negative controls) among participants of an HIV sentinel surveillance survey in six urban cities. The HCV infection was initially screened using anti-HCV ELISA and immunoblot assay, and thereafter confirmed by the HCV RNA qualitative assay. Among cases, no confirmed HCV infection was found while among controls, only two confirmed HCV infections were reported (0.62%). This matched case-control reports a very low probability of association between HCV and HIV co-infection and suggests a very low prevalence of HCV infection among MSM in Peru.

Author Notes

Reprints requests: Javier R. Lama, Investigaciones Medicas en Salud, Jr. Jose De La Torre Ugarte 166, Lima 14, Peru, Tel: +(51-1) 441-3993, Fax: +(51-1) 422-9425, E-mail: jrlama@inmensa.org.
  • 1

    Macdonald N, Dougan S, McGarrigle CA, Baster K, Rice BD, Evans BG, Fenton KA, 2004. Recent trends in diagnoses of HIV and other sexually transmitted infections in England and Wales among men who have sex with men. Sex Transm Infect 80 :492–497.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 2

    Alter MJ, 2002. Prevention of spread of hepatitis C. Hepatology 36 :S93–S98.

  • 3

    Bautista CT, Sanchez JL, Montano SM, Laguna-Torres VA, Lama JR, Kusunoki L, Manrique H, Acosta J, Montoya O, Tambare AM, Avila MM, Vinoles J, Aguayo N, Olson JG, Carr JK, 2004. Seroprevalence of and risk factors for HIV-1 infection among South American men who have sex with men. Sex Transm Infect 80 :498–504.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 4

    Lama JR, Lucchetti A, Suarez L, Laguna-Torres VA, Guanira JV, Pun M, Montano SM, Celum CL, Carr JK, Sanchez J, Bautista CT, Sanchez JL, 2006. Association of herpes simplex virus type 2 infection and syphilis with human immunodeficiency virus infection among men who have sex with men in Peru. J Infect Dis 194 :1459–1466.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5

    Alary M, Joly JR, Vincelette J, Lavoie R, Turmel B, Remis RS, 2005. Lack of evidence of sexual transmission of hepatitis C virus in a prospective cohort study of men who have sex with men. Am J Public Health 95 :502–505.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 6

    Rauch A, Rickenbach M, Weber R, Hirschel B, Tarr PE, Bucher HC, Vernazza P, Bernasconi E, Zinkernagel AS, Evison J, Furrer H, 2005. Unsafe sex and increased incidence of hepatitis C virus infection among HIV-infected men who have sex with men: the Swiss HIV Cohort Study. Clin Infect Dis 41 :395–402.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 7

    Eyster ME, Alter HJ, Aledort LM, Quan S, Hatzakis A, Goedert JJ, 1991. Heterosexual co-transmission of hepatitis C virus (HCV) and human immunodeficiency virus (HIV). Ann Intern Med 115 :764–768.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 8

    Sanchez JL, Sjogren MH, Callahan JD, Watts DM, Lucas C, Abdel-Hamid M, Constantine NT, Hyams KC, Hinostroza S, Figueroa-Barrios R, Cuthie JC, 2000. Hepatitis C in Peru: risk factors for infection, potential iatrogenic transmission, and genotype distribution. Am J Trop Med Hyg 63 :242–248.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9

    Pawlotsky JM, 2002. Use and interpretation of virological tests for hepatitis C. Hepatology 36 :S65–S73.

  • 10

    Alter MJ, Kuhnert WL, Finelli L, 2003. Guidelines for laboratory testing and result reporting of antibody to hepatitis C virus. Centers for Disease Control and Prevention. MMWR Recomm Rep 52 :1–13, 15 quiz CE1–4.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11

    Sayan M, Meric M, Mutlu B, Celebi S, Willke A, 2006. Low positive anti-HCV microparticle enzyme immunoassay results: do they predict hepatitis C virus infection? Mikrobiyol Bul 40 :81–84.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 12

    Buffington J, Murray PJ, Schlanger K, Shih L, Badsgard T, Hennessy RR, Wood R, Weisfuse IB, Gunn RA, 2007. Low prevalence of hepatitis C virus antibody in men who have sex with men who do not inject drugs. Public Health Rep 122 (Suppl 2):63–67.

    • PubMed
    • Search Google Scholar
    • Export Citation
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