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1
Franco-Paredes C, Santos-Preciado JI, 2006. Problem pathogens: prevention of malaria in travellers. Lancet Infect Dis 6 :139–149.
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2
Cunha BA, 2006. Typhoid fever: the temporal relations of key clinical diagnostic points. Lancet Infect Dis 6 :318–320.
-
3
McCarthy KM, Frean J, Loakes J, Liebowitz LD, 1999. Growth and maturation of Plasmodium falciparum in BacT/Alert blood culture system. Trans R Soc Trop Med Hyg 93 :272–274.
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4
Richalet G, Brenier-Pinchart MP, Bosseray A, Croize J, Pelloux H, 2002. Bactec 9240 alarm triggered by Plasmodium falciparum.Eur J Clin Microbiol Infect Dis 21 :244–245.
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5
Ziegler R, Johnscher I, Martus P, Lenhardt D, Just HM, 1998. Controlled clinical laboratory comparison of two supplemented aerobic and anaerobic media used in automated blood culture systems to detect bloodstream infections. J Clin Microbiol 36 :657–661.
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6
Qian Q, Tang YW, Kolbert CP, Torgerson CA, Hughes JG, Vetter EA, Harmsen WS, Montgomery SO, Cockerill FR III, Persing DH, 2001. Direct identification of bacteria from positive blood cultures by amplification and sequencing of the 16S rRNA gene: evaluation of Bactec 9240 instrument true-positive and false-positive results. J Clin Microbiol 39 :3578–3582.
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7
Grall M, Srivastava IK, Schmidt M, Garcia AM, Mauel J, Perrin LH, 1992. Plasmodium falciparum: identification and purification of the phosphoglycerate kinase of the malaria parasite. Exp Parasitol 75 :10–18.
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8
Badiaga S, Imbert G, La Scola B, Jean P, Delmont J, Brouqui P, 2005. Imported brucellosis associated with Plasmodium falciparum malaria in a traveler returning from the tropics. J Travel Med 12 :282–284.
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9
Bruneel F, Hocqueloux L, Alberti C, Wolff M, Chevret S, Bedos JP, Durand R, Le Bras J, Regnier B, Vachon F, 2003. The clinical spectrum of severe imported falciparum malaria in the intensive care unit: report of 188 cases in adults. Am J Respir Crit Care Med 167 :684–689.
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10
Khan MA, Mekan SF, Abbas Z, Smego RA Jr, 2005. Concurrent malaria and enteric fever in Pakistan. Singapore Med J 46 :635–638.
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11
Oundo JO, Muli F, Kariuki S, Waiyaki PG, Iijima Y, Berkley J, Kokwaro GO, Ngetsa CJ, Mwarumba S, Torto R, Lowe B, 2002. Non-typhi Salmonella in children with severe malaria. East Afr Med J 79 :633–639.
| Past two years | Past Year | Past 30 Days | |
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| Abstract Views | 124 | 105 | 9 |
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POSITIVE BLOOD CULTURE WITH PLASMODIUM FALCIPARUM: CASE REPORT
JUTTE J.C. DE VRIES
JUTTE J.C. DE VRIES
Department of Medical Microbiology, Department of Internal Medicine, Division of Infectious Diseases, and Department of Clinical Chemistry, University Medical Center Groningen, The Netherlands
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SANDER VAN ASSEN
SANDER VAN ASSEN
Department of Medical Microbiology, Department of Internal Medicine, Division of Infectious Diseases, and Department of Clinical Chemistry, University Medical Center Groningen, The Netherlands
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ANDRÉ B. MULDER
ANDRÉ B. MULDER
Department of Medical Microbiology, Department of Internal Medicine, Division of Infectious Diseases, and Department of Clinical Chemistry, University Medical Center Groningen, The Netherlands
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GREETJE A. KAMPINGA
GREETJE A. KAMPINGA
Department of Medical Microbiology, Department of Internal Medicine, Division of Infectious Diseases, and Department of Clinical Chemistry, University Medical Center Groningen, The Netherlands
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An adult traveler presented with fever and malaise after returning from Sierra Leone. Young trophozoites of Plasmodium falciparum were seen in a blood smear, with parasitemia being 10%. Moreover, blood cultures drawn on admission signaled as “positive” after 1 day of incubation, but no bacteria were seen in the Gram stain or were subcultured. A Giemsa-stained smear from the positive bottle contents yielded numerous pigmented, mature trophozoites of P. falciparum. This case indicates that, in patients with malaria, the growth of P. falciparum in blood cultures can result in “false”-positive blood cultures.
Author Notes
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1
Franco-Paredes C, Santos-Preciado JI, 2006. Problem pathogens: prevention of malaria in travellers. Lancet Infect Dis 6 :139–149.
-
2
Cunha BA, 2006. Typhoid fever: the temporal relations of key clinical diagnostic points. Lancet Infect Dis 6 :318–320.
-
3
McCarthy KM, Frean J, Loakes J, Liebowitz LD, 1999. Growth and maturation of Plasmodium falciparum in BacT/Alert blood culture system. Trans R Soc Trop Med Hyg 93 :272–274.
-
4
Richalet G, Brenier-Pinchart MP, Bosseray A, Croize J, Pelloux H, 2002. Bactec 9240 alarm triggered by Plasmodium falciparum.Eur J Clin Microbiol Infect Dis 21 :244–245.
-
5
Ziegler R, Johnscher I, Martus P, Lenhardt D, Just HM, 1998. Controlled clinical laboratory comparison of two supplemented aerobic and anaerobic media used in automated blood culture systems to detect bloodstream infections. J Clin Microbiol 36 :657–661.
-
6
Qian Q, Tang YW, Kolbert CP, Torgerson CA, Hughes JG, Vetter EA, Harmsen WS, Montgomery SO, Cockerill FR III, Persing DH, 2001. Direct identification of bacteria from positive blood cultures by amplification and sequencing of the 16S rRNA gene: evaluation of Bactec 9240 instrument true-positive and false-positive results. J Clin Microbiol 39 :3578–3582.
-
7
Grall M, Srivastava IK, Schmidt M, Garcia AM, Mauel J, Perrin LH, 1992. Plasmodium falciparum: identification and purification of the phosphoglycerate kinase of the malaria parasite. Exp Parasitol 75 :10–18.
-
8
Badiaga S, Imbert G, La Scola B, Jean P, Delmont J, Brouqui P, 2005. Imported brucellosis associated with Plasmodium falciparum malaria in a traveler returning from the tropics. J Travel Med 12 :282–284.
-
9
Bruneel F, Hocqueloux L, Alberti C, Wolff M, Chevret S, Bedos JP, Durand R, Le Bras J, Regnier B, Vachon F, 2003. The clinical spectrum of severe imported falciparum malaria in the intensive care unit: report of 188 cases in adults. Am J Respir Crit Care Med 167 :684–689.
-
10
Khan MA, Mekan SF, Abbas Z, Smego RA Jr, 2005. Concurrent malaria and enteric fever in Pakistan. Singapore Med J 46 :635–638.
-
11
Oundo JO, Muli F, Kariuki S, Waiyaki PG, Iijima Y, Berkley J, Kokwaro GO, Ngetsa CJ, Mwarumba S, Torto R, Lowe B, 2002. Non-typhi Salmonella in children with severe malaria. East Afr Med J 79 :633–639.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 124 | 105 | 9 |
| Full Text Views | 309 | 3 | 0 |
| PDF Downloads | 97 | 4 | 0 |