| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 591 | 221 | 26 |
| Full Text Views | 15 | 3 | 0 |
| PDF Downloads | 21 | 5 | 0 |
Arboviruses and Lemurs in Madagascar: Experimental Infection of Lemur Fulvus with Yellow Fever and West Nile Viruses
Francois Rodhain
Francois Rodhain
Laboratoire des Arbovirus, Unité d'Ecologie Virale, Institut Pasteur, 75015 Paris, France
Search for other papers by Francois Rodhain in
Current site
Google Scholar
PubMed
Search for other papers by Francois Rodhain in
Current site
Google Scholar
PubMed
Jean-Jacques Petter
Jean-Jacques Petter
Laboratoire d'Ecologie Générale, Museum National d'Histoire Naturelle, Brunoy, France
Search for other papers by Jean-Jacques Petter in
Current site
Google Scholar
PubMed
Search for other papers by Jean-Jacques Petter in
Current site
Google Scholar
PubMed
Roland Albignac
Roland Albignac
Laboratoire d'Ecologie Animale, Faculté des Sciences, 25035 Besançon, France
Search for other papers by Roland Albignac in
Current site
Google Scholar
PubMed
Search for other papers by Roland Albignac in
Current site
Google Scholar
PubMed
Pierre Coulanges
Pierre Coulanges
Institut Pasteur de Madagascar, B.P. 1274, Antananarivo, Madagascar
Search for other papers by Pierre Coulanges in
Current site
Google Scholar
PubMed
Search for other papers by Pierre Coulanges in
Current site
Google Scholar
PubMed
Claude Hannoun
Claude Hannoun
Laboratoire des Arbovirus, Unité d'Ecologie Virale, Institut Pasteur, 75015 Paris, France
Search for other papers by Claude Hannoun in
Current site
Google Scholar
PubMed
Search for other papers by Claude Hannoun in
Current site
Google Scholar
PubMed
In previous serological surveys of lemurs in Madagascar, antibodies against flaviviruses were frequently detected. To examine the epidemiological role of Lemur fulvus, experimental infections with yellow fever (YF) virus and West Nile (WN) virus were performed. YF and WN infections were clinically unapparent. A 3 to 4-day-long viremia, with moderate levels was observed with YF virus. WN virus, especially the strain isolated in Madagascar, provoked a 4 to 6-day-long viremia sufficient to infect Aedes aegypti. In all experiments, the antibody response was studied during the following weeks by 3 methods. The results led to the conclusion that Malagasy lemurs could act as amplifying hosts for WN virus present in Madagascar, and as hosts for YF virus if it were introduced on the island. The epidemiological role of these primates is discussed according to their ecology and their contact with potential mosquito vectors in forest areas of Madagascar.
Author Notes
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 591 | 221 | 26 |
| Full Text Views | 15 | 3 | 0 |
| PDF Downloads | 21 | 5 | 0 |