Dear Sir,
We have read with curiosity, as well as with alarm, the article by Zhang et al. on a human case of disseminated cysticercosis because of the intentional ingestion of Taenia eggs by a woman with the aim of losing weight.1 Tapeworms have been marketed as a weight loss product for over 100 years, and despite the known health risks, tapeworms continue to be advertised and sold today. Dieters swallow beef tapeworm cysticerci (Cysticercus bovis, the Taenia saginata metacestode), usually in the form of a pill. The theory is that the tapeworms will reach maturity in the intestine, and that the adult stage will absorb food. This could cause weight loss, along with possible symptoms such as diarrhea and vomiting.
According to the case report, the patient did not ingest any cysticerci, but rather the eggs of T. saginata contained in the pills. If the eggs were viable, they would turn into cysticerci, but only in intermediate hosts, cattle in the case of T. saginata. Therefore, these eggs would not have any effect in humans, which was the reason why the authors did not find any reference to the ingestion of Taenia eggs to lose weight. Likewise, the authors speculated that the ingested eggs could be T. solium, rather than T. saginata, as the patient developed disseminated cysticercosis, and among human Taenia tapeworms only the eggs of T. solium are infective for humans.1 In these speculations, T. asiatica, a species whose ability to cause human cysticercosis is still unknown,2 was not considered. If the egg providers identified the source of these eggs (T. saginata adult stage) through the morphology of the gravid proglottids, it should be considered that T. asiatica has the same gravid proglottid morphology as T. saginata. Taenia asiatica is present not only in China (where the case is reported) but also in many other Asian countries,3 although the country of origin of the eggs is apparently unknown. Likewise, T. asiatica cross-reacts with T. solium in the ELISA the authors used.4 Therefore, a molecular analysis of the patient’s cysticerci would have been necessary to assess the etiology of this case of disseminated cysticercosis. As no specific diagnostic technique was conducted, the possibility that T. asiatica was responsible should not be ruled out.
It would be hard to believe that the providers of the pills purposely supplied T. solium eggs for human consumption, considering the risk of dying of neurocysticercosis, as happened in an illustrative case with death after the intentional ingestion of T. solium eggs published in 1994.5 Thus, considering the consequences apparently derived from the ingestion of the pills the patient purchased, a molecular analysis of these eggs would have been desirable to take legal action against the company in case the eggs were T. solium, to prevent possible fatal cases of neurocysticercosis in other pill consumers.
REFERENCES
- 1.↑
Zhang HY, Wang GX, Xing YY, Xie MR, 2022. Case report: disseminated cysticercosis due to intentional ingestion of parasitic worm eggs for weight loss. Am J Trop Med Hyg 106: 710–713.
- 2.↑
Galán-Puchades MT, Fuentes MV, 2013. Taenia asiatica: the most neglected human Taenia and the possibility of cysticercosis. Korean J Parasitol 51: 51–54.
- 3.↑
Eom KS, Rim HJ, Jeon HK, 2020. Taenia asiatica: historical overview of taeniasis and cysticercosis with molecular characterization. Adv Parasitol 108: 133–173.
- 4.↑
Galán-Puchades MT, Fuentes MV, 2009. Diagnosis of human cysticercosis and Taenia asiatica. Am J Trop Med Hyg 81: 1165.
- 5.↑
Bourke GJ, Petana WB, 1994. Human Taenia cysticercosis: a bizarre mode of transmission. Trans R Soc Trop Med Hyg 88: 680.