ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Centers for Disease Control and Prevention, 2007. Health Information for International Travel 2008. Atlanta, GA: US Department of Health and Human Services, Public Health Service.
-
2.
TDR, 2005. Chagas' Disease. Tropical Disease Research: Progress 2003–2004. Seventeenth Programme Report of the United Nations Childrens' Fund/United Nations Devlopment Program/World Bank/World Health Organization Special Program for Research and Training in Tropical Diseases, 31–33.
-
3.
AABB, 2009. (Website Reference [101]) AABB: AABB Chagas' Biovigilance Network. Available at: www.aabb.org/Content/Programs_and_Services/Data_Center/Chagas/. Accessed October 25, 2009.
-
4.
Kjos SA, Snowded KF, Craig TM, Lewis B, Ronald N, Olson JK, 2008. Distribution and characterization of canine Chagas disease in Texas. Vet Parasitol 152: 249–256.
-
5.
Williams JT, Dick EJ Jr, VandeBerg JL, Hubbard GB, 2009. Natural Chagas disease in four baboons. J Med Primatol 38: 107–113.
-
6.
Barr SC, Brown CC, Dennis VA, Klei TR, 1991. The lesions and prevalence of Trypanosoma cruzi in opossums and armadillos from southern Louisiana. J Parasitol 77: 624–627.
-
7.
Brown EL, Roellig DM, Gomper ME, Monello RJ, Wenning KM, Gabriel MW, Yabsley MJ, 2009. Seroprevalence of Trypanosoma cruzi among twelve potential reservoir species from six states. Vector Borne Zoonotic Dis [Epub ahead of print].
-
8.
Clark CG, Pung OJ, 1994. Host specificity of ribosomal DNA variation in sylvatic Trypanosoma cruzi from North America. Mol Biochem Parasitol 66: 175–179.
-
9.
Barnabé C, Yaeger R, Pung O, Tibayrenc M, 2001. Trypanosoma cruzi: a considerable phylogenetic divergence indicates that the agent of Chagas disease is indigenous to the native fauna of the United States. Exp Parasitol 99: 73–79.
-
10.
Roellig DM, Brown EL, Barnabé C, Tibayrenc M, Steurer FJ, Yabsley MJ, 2008. Molecular typing of Trypanosoma cruzi isolates, United States. Emerg Infect Dis 14: 1123–1125.
-
11.
Bértoli M, Andó MH, de Ornelas Toledo MJ, de Araújo SM, Gomes ML, 2006. Infectivity for mice of Trypanosoma cruzi I and II strains isolated from different hosts. Parasitol Res 99: 7–13.
-
12.
Lisboa CV, Pinho AP, Monteiro RV, Jansen AM, 2007. Trypanosoma cruzi (kinetoplastida Trypanosomatidae): biological heterogeneity in the isolates derived from wild hosts. Exp Parasitol 116: 150–155.
-
13.
Wood SF, 1941. New localities for Trypanosoma cruzi Chagas in southwestern United States. Am J Trop Med Hyg 34: 1–13.
-
14.
Packchanian A, 1942. Reservoir hosts of Chagas' disease in the state of Texas: natural infection of nine-banded armadillo (Dasypus novemcinctus texanus), house mouse (Mus musculus), opossum (Didelphis virginiana), and wood rats (Neotoma micropus micropus), with Trypanosoma cruzi in the states of Texas. Am J Trop Med Hyg 22 (Suppl 1): 623–631.
-
15.
Walton BC, Bauman PM, Diamond LS, Herman CM, 1958. The isolation and identification of Trypanosoma cruzi from raccoons in Maryland. Am J Trop Med Hyg 7: 603–610.
-
16.
Olsen PF, Shoemaker JP, Turner HF, Hays KL, 1964. Incidence of Trypanosoma cruzi (Chagas) in wild vectors and reservoirs in east-central Alabama. J Parasitol 50: 599–603.
-
17.
Wood SF, 1975. Trypanosoma cruzi: new foci of enzootic Chagas' disease in California. Exp Parasitol 38: 153–160.
-
18.
John DT, Hoppe KL, 1986. Trypanosoma cruzi from wild raccoons in Oklahoma. Am J Vet Res 47: 1056–1059.
-
19.
Barr SC, Brown CC, Dennis VA, Klei TR, 1990. Infections of inbred mice with three Trypanosoma cruzi isolates from Louisiana mammals. J Parasitol 76: 918–921.
-
20.
Pietrzak SM, Pung OJ, 1998. Trypanosomiasis in raccoons from Georgia. J Wildl Dis 34: 132–136.
-
21.
Karsten V, Davis C, Kuhn R, 1992. Trypanosoma cruzi in wild raccoons and opossums in North Carolina. J Parasitol 78: 547–549.
-
22.
Roellig DM, Ellis AE, Yabsley MJ, 2009. Genetically different isolates of Trypanosoma cruzi elicit different infection dynamics in raccoons (Procyon lotor) and Virginia opossums (Didelphis virginiana). Int J Parasitol 39: 1603–1610.
-
23.
Brisse S, Verhoef J, Tibayrenc M, 2001. Characterisation of large and small subunit rRNA and min-exon genes further supports the distinction of six Trypanosoma cruzi lineages. Int J Parasitol 31: 1218–1226.
-
24.
Souto RP, Fernandes O, Macedo AM, Campbell DA, Zingales B, 1996. DNA markers define two major phylogenetic lineages of Trypanosoma cruzi. Mol Biochem Parasitol 83: 141–152.
-
25.
Castellani O, Ribeiro LV, Fernandes JF, 1967. Differentiation of Trypanosoma cruzi in culture. J Protozool 14: 447–451.
-
26.
Yeo M, Acosta N, Llewellyn M, Sánchez H, Adamson S, Miles GAJ, López E, Gonzáles N, Patterson JS, Gaunt MW, de Arias AR, Miles MA, 2005. Origins of Chagas disease: Didelphis species are natural hosts of Trypanosoma cruzi I and armadillo hosts of Trypanosoma cruzi II, including hybrids. Int J Parasitol 35: 225–233.
-
27.
Barnabé C, Yaegar R, Pung O, Tibayrenc M, 2001. Trypanosoma cruzi: a considerable phylogenetic divergence indicates that the agent of Chagas disease is indigenous to the native fauna of the United States. Exp Parasitol 99: 73–79.
-
28.
Wood SF, 1952. Mammal blood parasite records from Southwestern United States and Mexico. J Parasitol 38: 85–86.
-
29.
Ritter DM, Rowland EC, 1984. Corpus Christi strain-induced protection to Trypanosoma cruzi infection in C3H(He) mice: effective dose, time, route, and number of vaccinations. J Parasitol 70: 755–759.
| Past two years | Past Year | Past 30 Days | |
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| Abstract Views | 204 | 158 | 8 |
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Infectivity, Pathogenicity, and Virulence of Trypanosoma cruzi Isolates from Sylvatic Animals and Vectors, and Domestic Dogs from the United States in ICR Strain Mice and SD Strain Rats
Dawn M. Roellig
Dawn M. Roellig
Department of Infectious Diseases, College of Veterinary Medicine, Southeastern Cooperative Wildlife Disease Study, Department of Population Health, and D. B. Warnell School of Forestry and Natural Resources, The University of Georgia, Athens, Georgia
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Michael J. Yabsley
Michael J. Yabsley
Department of Infectious Diseases, College of Veterinary Medicine, Southeastern Cooperative Wildlife Disease Study, Department of Population Health, and D. B. Warnell School of Forestry and Natural Resources, The University of Georgia, Athens, Georgia
Search for other papers by Michael J. Yabsley in
Current site
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PubMed
Search for other papers by Michael J. Yabsley in
Current site
Google Scholar
PubMed
Trypanosoma cruzi, the causative agent of Chagas disease, is widespread in the southern United States. In addition to detection in numerous wildlife host species, cases have been diagnosed in domestic dogs and humans. In the current investigation, groups of laboratory mice [Crl:CD1 (ICR)] were inoculated with one of 18 United States T. cruzi isolates obtained from a wide host range to elucidate their infectivity, pathogenicity, and virulence. In addition, laboratory rats (SD strain) were inoculated with four isolates. Mice and rats were susceptible to infection with all strains, but no morbidity or mortality was noted, which indicates that these T. cruzi isolates from the United States had low virulence for laboratory mice and rats.
Author Notes
Financial support: This study was primarily supported by the National Institutes of Health grant R15 AI067304. Additional support was through funding provided to the Southeastern Cooperative Wildlife Disease Study by the Federal Aid to Wildlife Restoration Act (50 Stat. 917) and through sponsorship of the fish and wildlife agencies of Alabama, Arkansas, Florida, Georgia, Kansas, Kentucky, Louisiana, Maryland, Mississippi, Missouri, North Caroling, Oklahoma, Puerto Rico, South Carolina, Tennessee, Virginia, and West Virginia.
Authors' addresses: Dawn M. Roellig and Michael J. Yabsley, College of Veterinary Medicine, The University of Georgia, Wildlife Health Building, Athens, GA, E-mails: droellig@uga.edu and myabsley@uga.edu.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Centers for Disease Control and Prevention, 2007. Health Information for International Travel 2008. Atlanta, GA: US Department of Health and Human Services, Public Health Service.
-
2.
TDR, 2005. Chagas' Disease. Tropical Disease Research: Progress 2003–2004. Seventeenth Programme Report of the United Nations Childrens' Fund/United Nations Devlopment Program/World Bank/World Health Organization Special Program for Research and Training in Tropical Diseases, 31–33.
-
3.
AABB, 2009. (Website Reference [101]) AABB: AABB Chagas' Biovigilance Network. Available at: www.aabb.org/Content/Programs_and_Services/Data_Center/Chagas/. Accessed October 25, 2009.
-
4.
Kjos SA, Snowded KF, Craig TM, Lewis B, Ronald N, Olson JK, 2008. Distribution and characterization of canine Chagas disease in Texas. Vet Parasitol 152: 249–256.
-
5.
Williams JT, Dick EJ Jr, VandeBerg JL, Hubbard GB, 2009. Natural Chagas disease in four baboons. J Med Primatol 38: 107–113.
-
6.
Barr SC, Brown CC, Dennis VA, Klei TR, 1991. The lesions and prevalence of Trypanosoma cruzi in opossums and armadillos from southern Louisiana. J Parasitol 77: 624–627.
-
7.
Brown EL, Roellig DM, Gomper ME, Monello RJ, Wenning KM, Gabriel MW, Yabsley MJ, 2009. Seroprevalence of Trypanosoma cruzi among twelve potential reservoir species from six states. Vector Borne Zoonotic Dis [Epub ahead of print].
-
8.
Clark CG, Pung OJ, 1994. Host specificity of ribosomal DNA variation in sylvatic Trypanosoma cruzi from North America. Mol Biochem Parasitol 66: 175–179.
-
9.
Barnabé C, Yaeger R, Pung O, Tibayrenc M, 2001. Trypanosoma cruzi: a considerable phylogenetic divergence indicates that the agent of Chagas disease is indigenous to the native fauna of the United States. Exp Parasitol 99: 73–79.
-
10.
Roellig DM, Brown EL, Barnabé C, Tibayrenc M, Steurer FJ, Yabsley MJ, 2008. Molecular typing of Trypanosoma cruzi isolates, United States. Emerg Infect Dis 14: 1123–1125.
-
11.
Bértoli M, Andó MH, de Ornelas Toledo MJ, de Araújo SM, Gomes ML, 2006. Infectivity for mice of Trypanosoma cruzi I and II strains isolated from different hosts. Parasitol Res 99: 7–13.
-
12.
Lisboa CV, Pinho AP, Monteiro RV, Jansen AM, 2007. Trypanosoma cruzi (kinetoplastida Trypanosomatidae): biological heterogeneity in the isolates derived from wild hosts. Exp Parasitol 116: 150–155.
-
13.
Wood SF, 1941. New localities for Trypanosoma cruzi Chagas in southwestern United States. Am J Trop Med Hyg 34: 1–13.
-
14.
Packchanian A, 1942. Reservoir hosts of Chagas' disease in the state of Texas: natural infection of nine-banded armadillo (Dasypus novemcinctus texanus), house mouse (Mus musculus), opossum (Didelphis virginiana), and wood rats (Neotoma micropus micropus), with Trypanosoma cruzi in the states of Texas. Am J Trop Med Hyg 22 (Suppl 1): 623–631.
-
15.
Walton BC, Bauman PM, Diamond LS, Herman CM, 1958. The isolation and identification of Trypanosoma cruzi from raccoons in Maryland. Am J Trop Med Hyg 7: 603–610.
-
16.
Olsen PF, Shoemaker JP, Turner HF, Hays KL, 1964. Incidence of Trypanosoma cruzi (Chagas) in wild vectors and reservoirs in east-central Alabama. J Parasitol 50: 599–603.
-
17.
Wood SF, 1975. Trypanosoma cruzi: new foci of enzootic Chagas' disease in California. Exp Parasitol 38: 153–160.
-
18.
John DT, Hoppe KL, 1986. Trypanosoma cruzi from wild raccoons in Oklahoma. Am J Vet Res 47: 1056–1059.
-
19.
Barr SC, Brown CC, Dennis VA, Klei TR, 1990. Infections of inbred mice with three Trypanosoma cruzi isolates from Louisiana mammals. J Parasitol 76: 918–921.
-
20.
Pietrzak SM, Pung OJ, 1998. Trypanosomiasis in raccoons from Georgia. J Wildl Dis 34: 132–136.
-
21.
Karsten V, Davis C, Kuhn R, 1992. Trypanosoma cruzi in wild raccoons and opossums in North Carolina. J Parasitol 78: 547–549.
-
22.
Roellig DM, Ellis AE, Yabsley MJ, 2009. Genetically different isolates of Trypanosoma cruzi elicit different infection dynamics in raccoons (Procyon lotor) and Virginia opossums (Didelphis virginiana). Int J Parasitol 39: 1603–1610.
-
23.
Brisse S, Verhoef J, Tibayrenc M, 2001. Characterisation of large and small subunit rRNA and min-exon genes further supports the distinction of six Trypanosoma cruzi lineages. Int J Parasitol 31: 1218–1226.
-
24.
Souto RP, Fernandes O, Macedo AM, Campbell DA, Zingales B, 1996. DNA markers define two major phylogenetic lineages of Trypanosoma cruzi. Mol Biochem Parasitol 83: 141–152.
-
25.
Castellani O, Ribeiro LV, Fernandes JF, 1967. Differentiation of Trypanosoma cruzi in culture. J Protozool 14: 447–451.
-
26.
Yeo M, Acosta N, Llewellyn M, Sánchez H, Adamson S, Miles GAJ, López E, Gonzáles N, Patterson JS, Gaunt MW, de Arias AR, Miles MA, 2005. Origins of Chagas disease: Didelphis species are natural hosts of Trypanosoma cruzi I and armadillo hosts of Trypanosoma cruzi II, including hybrids. Int J Parasitol 35: 225–233.
-
27.
Barnabé C, Yaegar R, Pung O, Tibayrenc M, 2001. Trypanosoma cruzi: a considerable phylogenetic divergence indicates that the agent of Chagas disease is indigenous to the native fauna of the United States. Exp Parasitol 99: 73–79.
-
28.
Wood SF, 1952. Mammal blood parasite records from Southwestern United States and Mexico. J Parasitol 38: 85–86.
-
29.
Ritter DM, Rowland EC, 1984. Corpus Christi strain-induced protection to Trypanosoma cruzi infection in C3H(He) mice: effective dose, time, route, and number of vaccinations. J Parasitol 70: 755–759.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 204 | 158 | 8 |
| Full Text Views | 673 | 11 | 1 |
| PDF Downloads | 335 | 15 | 1 |