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Reference Manager
BibTeX
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-
1.
Rubinsky-Elefant G, Hirata CE, Yamamoto JH, Ferreira MU, 2010. Human toxocariasis: diagnosis, worldwide seroprevalences and clinical expression of the systemic and ocular forms. Ann Trop Med Parasitol 104: 3–23.
-
2.
Taylor MH, O’connor P, Keane C, Mulvihill E, Holland C, 1988. The expanded spectrum of toxocaral disease. Lancet 1: 692–695.
-
3.
Lim JH, 2012. Foodborne eosinophilia due to visceral larva migrans: a disease abandoned. J Korean Med Sci 27: 1–2.
-
4.
Pawlowski Z, 2001. Toxocariasis in humans: clinical expression and treatment dilemma. J Helminthol 75: 299–305.
-
5.
Smith H, Holland C, Taylor M, Magnaval JF, Schantz P, Maizels R, 2009. How common is human toxocariasis? Towards standardizing our knowledge. Trends Parasitol 25: 182–188.
-
6.
Akao N, Ohta N, 2007. Toxocariasis in Japan. Parasitol Int 56: 87–93.
-
7.
Woodhall DM, Eberhard ML, Parise ME, 2014. Neglected parasitic infections in the United States: toxocariasis. Am J Trop Med Hyg 90: 810–813.
-
8.
Park HY, Lee SU, Huh S, Kong Y, Magnaval JF, 2002. A seroepidemiological survey for toxocariasis in apparently healthy residents in Gangwon-do, Korea. Korean J Parasitol 40: 113–117.
-
9.
Kwon NH, Oh MJ, Lee SP, Lee BJ, Choi DC, 2006. The prevalence and diagnostic value of toxocariasis in unknown eosinophilia. Ann Hematol 85: 233–238.
-
10.
Kim YB, Ko YC, Jeon SH, Park HM, Shin WC, Lee YB, Ha KS, Shin DJ, Lim YH, Ryu JS, 2003. Toxocariasis: an unusual cause of cerebral infarction. J Korean Neurol Assoc 21: 651–654.
-
11.
Enko K et al. 2009. Fulminant eosinophilic myocarditis associated with visceral larva migrans caused by Toxocara canis infection. Circ J 73: 1344–1348.
-
12.
de Savigny DH, Voller A, Woodruff AW, 1979. Toxocariasis: serological diagnosis by enzyme immunoassay. J Clin Pathol 32: 284–288.
-
13.
Kappagoda S, Singh U, Blackburn BG, 2011. Antiparasitic therapy. Mayo Clin Proc 86: 561–583.
-
14.
Yoshikawa M, 2009. Duration of treatment with albendazole for hepatic toxocariasis. Nat Clin Pract Gastroenterol Hepatol 6: E1–E2.
-
15.
Ha KH, Song JE, Kim BS, Lee CH, 2016. Clinical characteristics and progression of liver abscess caused by toxocara. World J Hepatol 8: 757–761.
-
16.
Sturchler D, Schubarth P, Gualzata M, Gottstein B, Oettli A, 1989. Thiabendazole vs. albendazole in treatment of toxocariasis: a clinical trial. Ann Trop Med Parasitol 83: 473–478.
-
17.
Philips CA, Sharma CB, Pande A, Khan J, 2016. Space occupying lesion of the liver: the feline connection. Sch Acad J Biosci 4: 425–428
-
18.
Laroia ST, Rastogi A, Bihari C, Bhadoria AS, Sarin SK, 2016. Hepatic visceral larva migrans, a resilient entity on imaging: experience from a tertiary liver center. Trop Parasitol 6: 56–68.
-
19.
Lee KE, Suh KS, Lee NJ, Chang SH, Choi S, Kim SH, Lee KU, 2003. Laparoscopy-assisted hepatic resection in a patient with eosinophilic liver abscess by toxocaris cani involving liver. J Korean Surg Soc 64: 261–265.
-
20.
Mukund A, Arora A, Patidar Y, Mangla V, Bihari C, Rastogi A, Sarin SK, 2013. Eosinophilic abscesses: a new facet of hepatic visceral larva migrans. Abdom Imaging 38: 774–777.
-
21.
Treska V, Sutnar A, Mukensnabl P, Manakova T, Sedlacek D, Mirka H, Ferda J, 2011. Liver abscess in human toxocariasis. Bratisl Lek Listy 112: 644–647.
| Past two years | Past Year | Past 30 Days | |
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| Abstract Views | 195 | 123 | 10 |
| Full Text Views | 553 | 9 | 0 |
| PDF Downloads | 250 | 6 | 0 |
Space Occupying Lesion in the Liver Caused by Hepatic Visceral Larva Migrans: A Case Report
Kye-Yeung Park
Kye-Yeung Park
Department of Family Medicine, Hanyang University College of Medicine, Seoul, Korea;
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Hoon-Ki Park
Hoon-Ki Park
Department of Family Medicine, Hanyang University College of Medicine, Seoul, Korea;
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Hwan-Sik Hwang
Hwan-Sik Hwang
Department of Family Medicine, Hanyang University College of Medicine, Seoul, Korea;
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Jae-Sook Ryu
Jae-Sook Ryu
Department of Environmental Biology and Medical Parasitology, Hanyang University College of Medicine, Seoul, Korea;
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Kyeong-Geun Lee
Kyeong-Geun Lee
Department of Surgery, Hanyang University College of Medicine, Seoul, Korea;
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Ki-Seok Jang
Ki-Seok Jang
Department of Pathology Hanyang University College of Medicine, Seoul, Korea
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Visceral larva migrans (VLM) is one of the clinical syndromes of human toxocariasis. We report a case of hepatic VLM presenting preprandial malaise and epigastric discomfort in a 58-year-old woman drinking raw roe deer blood. The imaging studies of the abdomen showed a 74-mm hepatic mass featuring hepatic VLM. Anti–Toxocara canis immunoglobulin G (IgG) was observed in enzyme-linked immunosorbent assay (ELISA) and western blot. Despite anthelmintic treatment, the patient complained of newly developed cough and skin rash with severe eosinophilia. Hepatic lesion increased in size. The patient underwent an open left lobectomy of the liver. After the surgery, the patient was free of symptoms such as preprandial malaise, epigastric discomfort, cough, and skin rash. Laboratory test showed a normal eosinophilic count at postoperative 1 month, 6 months, 1 year, and 4 years. The initial optical density value of 2.55 of anti–T. canis IgG in ELISA was found to be negative (0.684) at postoperative 21 months. Our case report highlights that a high degree of clinical suspicion for hepatic VLM should be considered in a patient with a history of ingestion of raw food in the past, presenting severe eosinophilia and a variety of symptoms which reflect high worm burdens. Symptom remission, eosinophilia remission, and complete radiological resolution of lesions can be complete with surgery.
Author Notes
Authors’ addresses: Kye-Yeung Park, Hoon-Ki Park, and Hwan-Sik Hwang, Department of Family Medicine, Hanyang University College of Medicine, Seoul, Korea, E-mails: kyeyeung@naver.com, hoonkp@hanyang.ac.kr, and fmhwang@hanyang.ac.kr. Jae-Sook Ryu, Department of Environmental Biology and Medical Parasitology, Hanyang University College of Medicine, Seoul, Korea, E-mail: jsryu@hanyang.ac.kr. Kyeong-Geun Lee, Department of Surgery, Hanyang University College of Medicine, Seoul, Korea, E-mail: hepafel@hanyang.ac.kr. Ki-Seok Jang, Department of Pathology, Hanyang University College of Medicine, Seoul, Korea, E-mail: medartisan@hanyang.ac.kr.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Rubinsky-Elefant G, Hirata CE, Yamamoto JH, Ferreira MU, 2010. Human toxocariasis: diagnosis, worldwide seroprevalences and clinical expression of the systemic and ocular forms. Ann Trop Med Parasitol 104: 3–23.
-
2.
Taylor MH, O’connor P, Keane C, Mulvihill E, Holland C, 1988. The expanded spectrum of toxocaral disease. Lancet 1: 692–695.
-
3.
Lim JH, 2012. Foodborne eosinophilia due to visceral larva migrans: a disease abandoned. J Korean Med Sci 27: 1–2.
-
4.
Pawlowski Z, 2001. Toxocariasis in humans: clinical expression and treatment dilemma. J Helminthol 75: 299–305.
-
5.
Smith H, Holland C, Taylor M, Magnaval JF, Schantz P, Maizels R, 2009. How common is human toxocariasis? Towards standardizing our knowledge. Trends Parasitol 25: 182–188.
-
6.
Akao N, Ohta N, 2007. Toxocariasis in Japan. Parasitol Int 56: 87–93.
-
7.
Woodhall DM, Eberhard ML, Parise ME, 2014. Neglected parasitic infections in the United States: toxocariasis. Am J Trop Med Hyg 90: 810–813.
-
8.
Park HY, Lee SU, Huh S, Kong Y, Magnaval JF, 2002. A seroepidemiological survey for toxocariasis in apparently healthy residents in Gangwon-do, Korea. Korean J Parasitol 40: 113–117.
-
9.
Kwon NH, Oh MJ, Lee SP, Lee BJ, Choi DC, 2006. The prevalence and diagnostic value of toxocariasis in unknown eosinophilia. Ann Hematol 85: 233–238.
-
10.
Kim YB, Ko YC, Jeon SH, Park HM, Shin WC, Lee YB, Ha KS, Shin DJ, Lim YH, Ryu JS, 2003. Toxocariasis: an unusual cause of cerebral infarction. J Korean Neurol Assoc 21: 651–654.
-
11.
Enko K et al. 2009. Fulminant eosinophilic myocarditis associated with visceral larva migrans caused by Toxocara canis infection. Circ J 73: 1344–1348.
-
12.
de Savigny DH, Voller A, Woodruff AW, 1979. Toxocariasis: serological diagnosis by enzyme immunoassay. J Clin Pathol 32: 284–288.
-
13.
Kappagoda S, Singh U, Blackburn BG, 2011. Antiparasitic therapy. Mayo Clin Proc 86: 561–583.
-
14.
Yoshikawa M, 2009. Duration of treatment with albendazole for hepatic toxocariasis. Nat Clin Pract Gastroenterol Hepatol 6: E1–E2.
-
15.
Ha KH, Song JE, Kim BS, Lee CH, 2016. Clinical characteristics and progression of liver abscess caused by toxocara. World J Hepatol 8: 757–761.
-
16.
Sturchler D, Schubarth P, Gualzata M, Gottstein B, Oettli A, 1989. Thiabendazole vs. albendazole in treatment of toxocariasis: a clinical trial. Ann Trop Med Parasitol 83: 473–478.
-
17.
Philips CA, Sharma CB, Pande A, Khan J, 2016. Space occupying lesion of the liver: the feline connection. Sch Acad J Biosci 4: 425–428
-
18.
Laroia ST, Rastogi A, Bihari C, Bhadoria AS, Sarin SK, 2016. Hepatic visceral larva migrans, a resilient entity on imaging: experience from a tertiary liver center. Trop Parasitol 6: 56–68.
-
19.
Lee KE, Suh KS, Lee NJ, Chang SH, Choi S, Kim SH, Lee KU, 2003. Laparoscopy-assisted hepatic resection in a patient with eosinophilic liver abscess by toxocaris cani involving liver. J Korean Surg Soc 64: 261–265.
-
20.
Mukund A, Arora A, Patidar Y, Mangla V, Bihari C, Rastogi A, Sarin SK, 2013. Eosinophilic abscesses: a new facet of hepatic visceral larva migrans. Abdom Imaging 38: 774–777.
-
21.
Treska V, Sutnar A, Mukensnabl P, Manakova T, Sedlacek D, Mirka H, Ferda J, 2011. Liver abscess in human toxocariasis. Bratisl Lek Listy 112: 644–647.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 195 | 123 | 10 |
| Full Text Views | 553 | 9 | 0 |
| PDF Downloads | 250 | 6 | 0 |