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Reference Manager
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-
1
Galvao MA, Dumler JS, Mafra CL, Calic SB, Chamone CB, Cesarino FG, Olano JP, Walker DH, 2003. Fatal spotted fever rickettsiosis, Minas Gerais, Brazil. Emerg Infect Dis 9 :1402–1405.
-
2
Ripoll CM, Remondegui CE, Ordonez G, Arazamendi R, Fusaro H, Hyman MJ, Paddock CD, Zaki SR, Olson JG, Santos-Buch CA, 1999. Evidence of rickettsial spotted fever and ehrlichial infections in a subtropical territory of Jujuy, Argentina. Am J Trop Med Hyg 61 :350–354.
-
3
Segura F, Font B, 1982. Resurgence of Mediterranean spotted fever in Spain (letter). Lancet 2 :280.
-
4
Font-Creus B, Bella-Cueto F, Espejo-Arenas E, Vidal-Sanahuja R, Munoz-Espin T, Nolla-Salas M, Casagran-Borrell A, Mercade-Cuesta J, Segura-Porta F, 1985. Mediterranean spotted fever: a cooperative study of 227 cases. Rev Infect Dis 7 :635–642.
-
5
Raoult D, Tissot-Dupont H, Chicheportiche C, Peter O, Gilot B, Drancourt M, 1993. Mediterranean spotted fever in Marseille, France: correlation between prevalence of hospitalized patients, seroepidemiology, and prevalence of infected ticks in three different areas. Am J Trop Med Hyg 48 :249–256.
-
6
de Sousa R, Nobrega SD, Bacellar F, Torgal J, 2003. Mediterranean spotted fever in Portugal: risk factors for fatal outcome in 105 hospitalized patients. Ann N Y Acad Sci 990 :285–294.
-
7
Hemmersbach-Miller M, Parola P, Raoult D, Brouqui P, 2004. A homeless man with maculopapular rash who died in Marseille, France. Clin Infect Dis 38 :1412, 1493–1494.
-
8
Oster CN, Burke DS, Kenyon RH, Ascher MS, Harber P, Pedersen CE Jr, 1977. Laboratory-acquired Rocky Mountain spotted fever. The hazard of aerosol transmission. N Engl J Med 297 :859–863.
-
9
Wells GM, Woodward TE, Fiset P, Hornick RB, 1978. Rocky Mountain spotted fever caused by blood transfusion. JAMA 239 :2763–2765.
-
10
Burgdorfer W, 1977. Tick-borne diseases in the United States: Rocky Mountain spotted fever and Colorado tick fever. A review. Acta Trop 34 :103–126.
-
11
Raoult D, Roux V, 1997. Rickettsioses as paradigms of new or emerging infectious diseases. Clin Microbiol Rev 10 :694–719.
-
12
Liu WT, 1940. Studies on the origin of typhus epidemics in North China. 1. Murine typhus rickettsiae isolated from body lice in the garments of a sporadic case. Am J Trop Med 21 :507–523.
-
13
Houhamdi L, Fournier PE, Fang R, Raoult D, 2003. An experimental model of human body louse infection with Rickettsia typhi. Ann N Y Acad Sci 990 :617–627.
-
14
Houhamdi L, Fournier PE, Fang R, Lepidi H, Raoult D, 2002. An experimental model of human body louse infection with Rickettsia prowazekii. J Infect Dis 186 :1639–1646.
-
15
Fournier PE, Minnick MF, Lepidi H, Salvo E, Raoult D, 2001. Experimental model of human body louse infection using green fluorescent protein-expressing Bartonella quintana. Infect Immun 69 :1876–1879.
-
16
Wike DA, Tallent G, Peacock MG, Ormsbee RA, 1972. Studies of the rickettsial plaque assay technique. Infect Immun 5 :715–722.
-
17
Roux V, Fournier PE, Raoult D, 1996. Differentiation of spotted fever group rickettsiae by sequencing and analysis of restriction fragment length polymorphism of PCR amplified DNA of the gene encoding the protein rOmpA. J Clin Microbiol 34 :2058–2065.
-
18
Greer CE, Peterson SL, Kiviat NB, Manos MM, 1991. PCR amplification from paraffin-embedded tissues. Effects of fixative and fixation time. Am J Clin Pathol 95 :117–124.
-
19
Fenollar F, Raoult D, 1999. Diagnosis of rickettsial diseases using samples dried on blotting paper. Clin Diagn Lab Immunol 6 :483–488.
-
20
La Scola B, Fournier PE, Brouqui P, Raoult D, 2001. Detection and culture of Bartonella quintana, Serratia marcescens and Acinetobacter spp. from decontaminated human body lice. J Clin Microbiol 39 :1707–1709.
-
21
Marrero M, Raoult D, 1989. Centrifugation-shell vial technique for rapid detection of Mediterranean spotted fever rickettsia in blood culture. Am J Trop Med Hyg 40 :197–199.
-
22
DeSalle R, Gatesy J, Wheeler W, Grimaldi D, 1992. DNA sequences from a fossil termite in Oligo-Miocene amber and their phylogenetic implications. Science 257 :1933–1936.
-
23
Xu WB, Raoult D, 1998. Taxonomic relationships among spotted fever group Rickettsiae as revealed by antigenic analysis with monoclonal antibodies. J Clin Microbiol 36 :887–896.
-
24
Houhamdi L, Raoult D, 2006. Experimental infection of human body lice with Acinetobacter baumannii. Am J Trop Med Hyg 74 :526–531.
-
25
Teysseire N, Chiche-Portiche C, Raoult D, 1992. Intracellular movements of Rickettsia conorii and R. typhi based on actin polymerization. Res Microbiol 143 :821–829.
-
26
Weyer F, 1978. Rickettsiae and lice. Kazar J, Ormsbee R, Tarasevich I, eds. Rickettsiae and Rickettsial Diseases. Veda, Bratislava, Slovakia: Publishing House of Slovak Academy of Sciences, 515–522.
-
27
Taylor JP, Istre GR, McChesney TC, 1988. The epidemiology of Rocky Mountain spotted fever in Arkansas, Oklahoma, and Texas, 1981 through 1985. Am J Epidemiol 127 :1295–1301.
-
28
Lange JV, Walker DH, Wester TB, 1982. Documented Rocky Mountain spotted fever in wintertime. JAMA 247 :2403–2404.
-
29
Tringali G, Occhino C, Mansueto S, Walker DH, Raoult D, 1986. Fièvre boutonneuse méditerranéenne diagnostiquée pendant la saison froide: quatre cas. Med Mal Infect 3 :183–184.
-
30
Brouqui P, La Scola B, Roux V, Raoult D, 1999. Chronic Bartonella quintana bacteremia in homeless patients. New Engl J Med 340 :184–189.
-
31
Zanetti G, Francioli P, Tagan D, Paddock CD, Zaki SR, 1998. Imported epidemic typhus. Lancet 352 :1709.
-
32
Stein A, Purgus R, Olmer M, Raoult D, 1999. Brill-Zinsser disease in France. Lancet 353 :1936.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 173 | 133 | 15 |
| Full Text Views | 111 | 4 | 2 |
| PDF Downloads | 49 | 6 | 4 |
EXPERIMENTALLY INFECTED HUMAN BODY LICE (PEDICULUS HUMANUS HUMANUS) AS VECTORS OF RICKETTSIA RICKETTSII AND RICKETTSIA CONORII IN A RABBIT MODEL
LINDA HOUHAMDI
LINDA HOUHAMDI
Unité des Rickettsies, Institut Fédératif de Recherche 48, Centre National de Recherche Scientifique, Unité Mixte de Recherche 6020, Université de la Méditerranée, Faculté de Médecine, Marseille, France
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DIDIER RAOULT
DIDIER RAOULT
Unité des Rickettsies, Institut Fédératif de Recherche 48, Centre National de Recherche Scientifique, Unité Mixte de Recherche 6020, Université de la Méditerranée, Faculté de Médecine, Marseille, France
Search for other papers by DIDIER RAOULT in
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The human body louse, the natural vector of Rickettsia prowazekii, is able to experimentally transmit the normally flea-borne rickettsia R. typhi, suggesting that the relationships between the body louse and rickettsiae are not specific. We used our experimental infection model to test the ability of body lice to transmit two prevalent tick-borne rickettsiae. Each of two rabbits was made bacteremic by injecting intravenously 2 × 106 plaque-forming units of either R. rickettsii or R. conorii. Four hundred body lice were infected by feeding on the bacteremic rabbit and were compared with 400 uninfected lice. Each louse group was fed once a day on a separate seronegative rabbit. The survival of infected lice was not different from that of uninfected controls. Lice remained infected for their lifespan, excreted R. rickettsii and R. conorii in their feces, but did not transmit the infection to their progeny. The nurse rabbit of uninfected lice remained asymptomatic and seronegative. Those rabbits used to feed infected lice developed bacteremia and seroconverted. Although the body louse is not a known vector of spotted fevers, it was able in our study to acquire, maintain, and transmit both R. rickettsii and R. conorii.
Author Notes
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1
Galvao MA, Dumler JS, Mafra CL, Calic SB, Chamone CB, Cesarino FG, Olano JP, Walker DH, 2003. Fatal spotted fever rickettsiosis, Minas Gerais, Brazil. Emerg Infect Dis 9 :1402–1405.
-
2
Ripoll CM, Remondegui CE, Ordonez G, Arazamendi R, Fusaro H, Hyman MJ, Paddock CD, Zaki SR, Olson JG, Santos-Buch CA, 1999. Evidence of rickettsial spotted fever and ehrlichial infections in a subtropical territory of Jujuy, Argentina. Am J Trop Med Hyg 61 :350–354.
-
3
Segura F, Font B, 1982. Resurgence of Mediterranean spotted fever in Spain (letter). Lancet 2 :280.
-
4
Font-Creus B, Bella-Cueto F, Espejo-Arenas E, Vidal-Sanahuja R, Munoz-Espin T, Nolla-Salas M, Casagran-Borrell A, Mercade-Cuesta J, Segura-Porta F, 1985. Mediterranean spotted fever: a cooperative study of 227 cases. Rev Infect Dis 7 :635–642.
-
5
Raoult D, Tissot-Dupont H, Chicheportiche C, Peter O, Gilot B, Drancourt M, 1993. Mediterranean spotted fever in Marseille, France: correlation between prevalence of hospitalized patients, seroepidemiology, and prevalence of infected ticks in three different areas. Am J Trop Med Hyg 48 :249–256.
-
6
de Sousa R, Nobrega SD, Bacellar F, Torgal J, 2003. Mediterranean spotted fever in Portugal: risk factors for fatal outcome in 105 hospitalized patients. Ann N Y Acad Sci 990 :285–294.
-
7
Hemmersbach-Miller M, Parola P, Raoult D, Brouqui P, 2004. A homeless man with maculopapular rash who died in Marseille, France. Clin Infect Dis 38 :1412, 1493–1494.
-
8
Oster CN, Burke DS, Kenyon RH, Ascher MS, Harber P, Pedersen CE Jr, 1977. Laboratory-acquired Rocky Mountain spotted fever. The hazard of aerosol transmission. N Engl J Med 297 :859–863.
-
9
Wells GM, Woodward TE, Fiset P, Hornick RB, 1978. Rocky Mountain spotted fever caused by blood transfusion. JAMA 239 :2763–2765.
-
10
Burgdorfer W, 1977. Tick-borne diseases in the United States: Rocky Mountain spotted fever and Colorado tick fever. A review. Acta Trop 34 :103–126.
-
11
Raoult D, Roux V, 1997. Rickettsioses as paradigms of new or emerging infectious diseases. Clin Microbiol Rev 10 :694–719.
-
12
Liu WT, 1940. Studies on the origin of typhus epidemics in North China. 1. Murine typhus rickettsiae isolated from body lice in the garments of a sporadic case. Am J Trop Med 21 :507–523.
-
13
Houhamdi L, Fournier PE, Fang R, Raoult D, 2003. An experimental model of human body louse infection with Rickettsia typhi. Ann N Y Acad Sci 990 :617–627.
-
14
Houhamdi L, Fournier PE, Fang R, Lepidi H, Raoult D, 2002. An experimental model of human body louse infection with Rickettsia prowazekii. J Infect Dis 186 :1639–1646.
-
15
Fournier PE, Minnick MF, Lepidi H, Salvo E, Raoult D, 2001. Experimental model of human body louse infection using green fluorescent protein-expressing Bartonella quintana. Infect Immun 69 :1876–1879.
-
16
Wike DA, Tallent G, Peacock MG, Ormsbee RA, 1972. Studies of the rickettsial plaque assay technique. Infect Immun 5 :715–722.
-
17
Roux V, Fournier PE, Raoult D, 1996. Differentiation of spotted fever group rickettsiae by sequencing and analysis of restriction fragment length polymorphism of PCR amplified DNA of the gene encoding the protein rOmpA. J Clin Microbiol 34 :2058–2065.
-
18
Greer CE, Peterson SL, Kiviat NB, Manos MM, 1991. PCR amplification from paraffin-embedded tissues. Effects of fixative and fixation time. Am J Clin Pathol 95 :117–124.
-
19
Fenollar F, Raoult D, 1999. Diagnosis of rickettsial diseases using samples dried on blotting paper. Clin Diagn Lab Immunol 6 :483–488.
-
20
La Scola B, Fournier PE, Brouqui P, Raoult D, 2001. Detection and culture of Bartonella quintana, Serratia marcescens and Acinetobacter spp. from decontaminated human body lice. J Clin Microbiol 39 :1707–1709.
-
21
Marrero M, Raoult D, 1989. Centrifugation-shell vial technique for rapid detection of Mediterranean spotted fever rickettsia in blood culture. Am J Trop Med Hyg 40 :197–199.
-
22
DeSalle R, Gatesy J, Wheeler W, Grimaldi D, 1992. DNA sequences from a fossil termite in Oligo-Miocene amber and their phylogenetic implications. Science 257 :1933–1936.
-
23
Xu WB, Raoult D, 1998. Taxonomic relationships among spotted fever group Rickettsiae as revealed by antigenic analysis with monoclonal antibodies. J Clin Microbiol 36 :887–896.
-
24
Houhamdi L, Raoult D, 2006. Experimental infection of human body lice with Acinetobacter baumannii. Am J Trop Med Hyg 74 :526–531.
-
25
Teysseire N, Chiche-Portiche C, Raoult D, 1992. Intracellular movements of Rickettsia conorii and R. typhi based on actin polymerization. Res Microbiol 143 :821–829.
-
26
Weyer F, 1978. Rickettsiae and lice. Kazar J, Ormsbee R, Tarasevich I, eds. Rickettsiae and Rickettsial Diseases. Veda, Bratislava, Slovakia: Publishing House of Slovak Academy of Sciences, 515–522.
-
27
Taylor JP, Istre GR, McChesney TC, 1988. The epidemiology of Rocky Mountain spotted fever in Arkansas, Oklahoma, and Texas, 1981 through 1985. Am J Epidemiol 127 :1295–1301.
-
28
Lange JV, Walker DH, Wester TB, 1982. Documented Rocky Mountain spotted fever in wintertime. JAMA 247 :2403–2404.
-
29
Tringali G, Occhino C, Mansueto S, Walker DH, Raoult D, 1986. Fièvre boutonneuse méditerranéenne diagnostiquée pendant la saison froide: quatre cas. Med Mal Infect 3 :183–184.
-
30
Brouqui P, La Scola B, Roux V, Raoult D, 1999. Chronic Bartonella quintana bacteremia in homeless patients. New Engl J Med 340 :184–189.
-
31
Zanetti G, Francioli P, Tagan D, Paddock CD, Zaki SR, 1998. Imported epidemic typhus. Lancet 352 :1709.
-
32
Stein A, Purgus R, Olmer M, Raoult D, 1999. Brill-Zinsser disease in France. Lancet 353 :1936.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 173 | 133 | 15 |
| Full Text Views | 111 | 4 | 2 |
| PDF Downloads | 49 | 6 | 4 |