Author:
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1
Holder AA, 1988. The precursor to major merozoite surface antigens: structure and role in immunity. Prog Allergy 41 :72–97.
-
2
Tanabe K, Mackay M, Goman M, Scaife JG, 1987. Allelic dimorphism in a surface antigen gene of the malaria parasite Plasmodium falciparum.J Mol Biol 195 :273–287.
-
3
Kemp DJ, Cowman AF, Walliker D, 1990. Genetic diversity in Plasmodium falciparum.Adv Parasitol 29 :75–149.
-
4
Ferreira MU, Qing L, Zhou M, Masatsugu K, Kaneko O, Van Thien H, Isomura S, Tanabe K, Kawamoto F, 1998. Stable patterns of allelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from southern Vietnam. J Eukaryot Microbiol 45 :131–136.
-
5
Ferreira MU, Liu QL, Kimura M, Ndawi BT, Tanabe K, Kawamoto F, 1998. Allelic diversity in the merozoite surface protein-1 and epidemiology of multiple-clone Plasmodium falciparum infections in northern Tanzania. J Parasitol 84 :1286–1289.
-
6
Ferreira MU, Liu Q, Kaneko O, Kimura M, Tanabe K, Kimura EA, Katzin AM, Isomura S, Kawamoto F, 1998. Allelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from the southwestern Brazilian Amazon. Am J Trop Med Hyg 59 :474–480.
-
7
Conway DJ, Roper C, Odauola AMJ, Arnot DE, Kremsner PG, Grobusch MP, Curtis C, Greenwood BM, 1999. High recombination rate in natural populations of Plasmodiium falciparum.Proc Nat Acad Sci USA 96 :4506–4511.
-
8
McBride JS, Newbold CI, Anand R, 1985. Polymorphism of a high molecular weight schizont antigen of human malaria parasite Plasmodium falciparum.J Exp Med 161 :160–180.
-
9
Kaneko O, Kimura M, Kawamoto F, Ferreira MU, Tanabe K, 1997. Plasmodium falciparum: allelic variation in the merozoite surface protein-1 in wild isolates from southern Vietnam. Exp Parasitol 86 :45–57.
-
10
Qari SH, Shi Y-P, Goldman IF, Nahlen BL, Tibayrenc M, Lal AA, 1998. Predicted and observed alleles of Plasmodium falciparum merozoite surface protein-1 (MSP-1), a potential malaria vaccine antigen. Mol Biochem Parasitol 92 :241–252.
-
11
Carrasquilla G, Banguero M, Sanchez P, Carvajal F, Barker RH Jr, Gervais GW, Algarin E, Serrano A, 2000. Epidemiologic tools for malaria surveillance in an urban setting of low endemicity along the Colombian Pacific Coast. Am J Trop Med Hyg 62 :132–137.
-
12
Gonzalez JM, Olano V, Vergara J, Arevalo-Herrera M, Carrasquilla G, Herrera S, Lopez JA, 1997. Unstable, low-level transmission of malaria on the Colombian Pacific Coast. Ann Trop Med Parasitol 91 :349–358.
-
13
Mendez F, Carrasquilla G, 1995. Epidemiología de la malaria en el área urbana de Buenaventura: análisis de la ocurrencia en el periodo 1987–1993. Colombia Med 26 :77–85.
-
14
Status Report on Malaria Programs in the Americas, (Based on 2001 data). PAHO/HCP/HCT/M217/02. 26th Pan American Sanitary Conference, 54th Session of the Regional Committee, Pan American Health Organization, World Health Organization. September 5, 2002, 10.
-
15
Gomez D, Chaparro J, Rubiano C, Orfa RM, Wasserman M, 2002. Genetic diversity of Plasmodium falciparum field samples from isolated Colombian village. Am J Trop Med Hyg 67 :611–616.
-
16
Tolle R, Bujard H, Cooper JA, 1995. Plasmodium falciparum: variations within the C-terminal region of merozoite surface antigen-1. Exp Parasitol 68 :470–473.
-
17
Kaneko O, Jongwutiwes S, Kimura M, Kanbara H, Ishii A, Tanabe K, 1996. Plasmodium falciparum: variation in block 4 of the precursor to the major merozoite surface proteins in natural populations. Exp Parasitol 84 :92–95.
-
18
da Silveira LA, Dorta MI, Kimura E, Katzin AM, Kawamoto F, Tanabe K, Ferreira M, 1999. Allelic diversity and antibody recognition of Plasmodium falciparum merozoite surface protein-1 during hypoendemic malaria transmission in the Brazilian Amazon region. Infect Immun 67 :5906–5916.
-
19
Kimbi HK, Tetteh KKA, Polley SD, Conway DJ, 2004. Cross-sectional study of specific antibodies to a polymorphic Plasmodium falciparum antigen and of parasite antigen genotypes in school children on the slope of Mount Cameroon. Trans Rl Soc Trop Med Hyg 98 :284–289.
-
20
Conway DJ, Rosario V, Oduola AMJ, Salako LA, Greenwood BM, McBride JS, 1991. Plasmodium falciparum intragenic recombination and nonrandom association between polymorphic domains of the precursor to the major merozoite surface antigens. Exp Parasitol 73 :469–480.
-
21
Lee EAM, Flanagan KL, Odihiambo K, Reece WHH, Potter C, Bailey R, Marsh K, Pinder M, Hill AVS, Plebanski M, 2001. Identification of frequenly recognized dimorphic T-cell epitopes in Plasmodium falciparum merozoite surface protein-1 in west and east Africans: Lack of correlation of immune recognition and allelic prevalence. Am J Trop Med Hyg 64 :194–203.
-
22
Snewin VA, Herrera M, Sanchez G, Scherf A, Langsley G, Herrera S, 1991. Polymorphism of the alleles of the merozoite surface antigens MSA1 and MSA2 in Plasmodium falciparum wild isolates from Colombia. Mol Biomed Parasitol 49 :265–276.
-
23
Montoya L, Maestre A, Carmona J, Lopes D, Do Rosario V, Blair S, 2003. Plasmodium falciparum: diversity studies of isolates from two Colombian regions with different endemicity. Exp Parasitol 104 :14–19.
-
24
Ntoumi F, Contamin H, Rogier C, Bonneloy S, Trape JF, Merceteau-Puijalon O, 1995. Age-dependent carriage of multiple Plasmodium falciparum merozoite surface Antigen-2 alleles in asymptomatic malaria infections. Am J Trop Med Hyg 52 :81–88.
-
25
Takahata N, Nei M, 1990. Allelic geneology under over-dominant and frequency-dependent selection and polymorphism of major histocompatiblity complex loci. Genetics 124 :967–978.
-
26
Hughes AL, 1992. Positive selection and interallelic recombination at the merozoite surface antigen-1 (MSA-1) locus of Plasmodium falciparum.Mol Biol Evol 9 :381–393.
-
27
Ferreira MU, Kaneko O, Masatsugu K, Qing L, Kawamoto F, Tanabe K, 1998d. Allelic diversity at the merozoite surface protein-1 (MSP-1) locus in natural Plasmodium falciparum populations: a brief overview. Mem Inst Oswaldo Cruz 93 :631–638.
-
28
Ferreira MU, Ribeiro WL, Tonon AP, Kawamoto F, Rich SM, 2003. Sequence diversity and evolution of the malaria vaccine candidate merozoite surface protein-1 (MSP-1) of Plasmodium falciparum.Gene 304 :65–75.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 448 | 362 | 55 |
| Full Text Views | 330 | 20 | 3 |
| PDF Downloads | 46 | 11 | 0 |
RESTRICTED GENETIC DIVERSITY OF PLASMODIUM FALCIPARUM MAJOR MEROZOITE SURFACE PROTEIN 1 IN ISOLATES FROM COLOMBIA
ZILKA I. TERRIENTES
ZILKA I. TERRIENTES
Department of Microbiology, Faculty of Medicine, University of Panama, Panama City, Panama; Department of Tropical Medicine and Medical Microbiology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii; Malaria Vaccine and Drug Development Center, Cali, Colombia; Instituto de Inmunología Universidad del Valle, Cali, Colombia
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JUANA VERGARA
JUANA VERGARA
Department of Microbiology, Faculty of Medicine, University of Panama, Panama City, Panama; Department of Tropical Medicine and Medical Microbiology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii; Malaria Vaccine and Drug Development Center, Cali, Colombia; Instituto de Inmunología Universidad del Valle, Cali, Colombia
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KENTON KRAMER
KENTON KRAMER
Department of Microbiology, Faculty of Medicine, University of Panama, Panama City, Panama; Department of Tropical Medicine and Medical Microbiology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii; Malaria Vaccine and Drug Development Center, Cali, Colombia; Instituto de Inmunología Universidad del Valle, Cali, Colombia
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SÓCRATES HERRERA
SÓCRATES HERRERA
Department of Microbiology, Faculty of Medicine, University of Panama, Panama City, Panama; Department of Tropical Medicine and Medical Microbiology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii; Malaria Vaccine and Drug Development Center, Cali, Colombia; Instituto de Inmunología Universidad del Valle, Cali, Colombia
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SANDRA P. CHANG
SANDRA P. CHANG
Department of Microbiology, Faculty of Medicine, University of Panama, Panama City, Panama; Department of Tropical Medicine and Medical Microbiology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii; Malaria Vaccine and Drug Development Center, Cali, Colombia; Instituto de Inmunología Universidad del Valle, Cali, Colombia
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The merozoite surface protein 1 (MSP-1) gene of Plasmodium falciparum encodes a major immune target under development as a malaria vaccine. In this study, we typed MSP-1 variable regions of parasites obtained from Buenaventura, Colombia. Four MSP-1 gene types were detected corresponding to prototype and recombinant K1 and MAD20 block 4 sequences. In contrast to variability within block 4, blocks 2, 6, and 16–17 corresponded exclusively to the MAD20 allelic type. Most (80%) blood samples contained multiple MSP-1 gene types. The presence of four MSP-1 variants within block 4 against a MAD20 background indicates that current P. falciparum populations in Buenaventura are derived from parasites expressing K1 and MAD20 alleles, some of which underwent two recombination events within or flanking block 4. Restricted MSP-1 diversity appears to be relatively stable in Buenaventura and suggests that selection has resulted in the dominance of the MAD20 type in most of the polymorphic blocks with the exception of block 4.
Author Notes
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
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-
1
Holder AA, 1988. The precursor to major merozoite surface antigens: structure and role in immunity. Prog Allergy 41 :72–97.
-
2
Tanabe K, Mackay M, Goman M, Scaife JG, 1987. Allelic dimorphism in a surface antigen gene of the malaria parasite Plasmodium falciparum.J Mol Biol 195 :273–287.
-
3
Kemp DJ, Cowman AF, Walliker D, 1990. Genetic diversity in Plasmodium falciparum.Adv Parasitol 29 :75–149.
-
4
Ferreira MU, Qing L, Zhou M, Masatsugu K, Kaneko O, Van Thien H, Isomura S, Tanabe K, Kawamoto F, 1998. Stable patterns of allelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from southern Vietnam. J Eukaryot Microbiol 45 :131–136.
-
5
Ferreira MU, Liu QL, Kimura M, Ndawi BT, Tanabe K, Kawamoto F, 1998. Allelic diversity in the merozoite surface protein-1 and epidemiology of multiple-clone Plasmodium falciparum infections in northern Tanzania. J Parasitol 84 :1286–1289.
-
6
Ferreira MU, Liu Q, Kaneko O, Kimura M, Tanabe K, Kimura EA, Katzin AM, Isomura S, Kawamoto F, 1998. Allelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from the southwestern Brazilian Amazon. Am J Trop Med Hyg 59 :474–480.
-
7
Conway DJ, Roper C, Odauola AMJ, Arnot DE, Kremsner PG, Grobusch MP, Curtis C, Greenwood BM, 1999. High recombination rate in natural populations of Plasmodiium falciparum.Proc Nat Acad Sci USA 96 :4506–4511.
-
8
McBride JS, Newbold CI, Anand R, 1985. Polymorphism of a high molecular weight schizont antigen of human malaria parasite Plasmodium falciparum.J Exp Med 161 :160–180.
-
9
Kaneko O, Kimura M, Kawamoto F, Ferreira MU, Tanabe K, 1997. Plasmodium falciparum: allelic variation in the merozoite surface protein-1 in wild isolates from southern Vietnam. Exp Parasitol 86 :45–57.
-
10
Qari SH, Shi Y-P, Goldman IF, Nahlen BL, Tibayrenc M, Lal AA, 1998. Predicted and observed alleles of Plasmodium falciparum merozoite surface protein-1 (MSP-1), a potential malaria vaccine antigen. Mol Biochem Parasitol 92 :241–252.
-
11
Carrasquilla G, Banguero M, Sanchez P, Carvajal F, Barker RH Jr, Gervais GW, Algarin E, Serrano A, 2000. Epidemiologic tools for malaria surveillance in an urban setting of low endemicity along the Colombian Pacific Coast. Am J Trop Med Hyg 62 :132–137.
-
12
Gonzalez JM, Olano V, Vergara J, Arevalo-Herrera M, Carrasquilla G, Herrera S, Lopez JA, 1997. Unstable, low-level transmission of malaria on the Colombian Pacific Coast. Ann Trop Med Parasitol 91 :349–358.
-
13
Mendez F, Carrasquilla G, 1995. Epidemiología de la malaria en el área urbana de Buenaventura: análisis de la ocurrencia en el periodo 1987–1993. Colombia Med 26 :77–85.
-
14
Status Report on Malaria Programs in the Americas, (Based on 2001 data). PAHO/HCP/HCT/M217/02. 26th Pan American Sanitary Conference, 54th Session of the Regional Committee, Pan American Health Organization, World Health Organization. September 5, 2002, 10.
-
15
Gomez D, Chaparro J, Rubiano C, Orfa RM, Wasserman M, 2002. Genetic diversity of Plasmodium falciparum field samples from isolated Colombian village. Am J Trop Med Hyg 67 :611–616.
-
16
Tolle R, Bujard H, Cooper JA, 1995. Plasmodium falciparum: variations within the C-terminal region of merozoite surface antigen-1. Exp Parasitol 68 :470–473.
-
17
Kaneko O, Jongwutiwes S, Kimura M, Kanbara H, Ishii A, Tanabe K, 1996. Plasmodium falciparum: variation in block 4 of the precursor to the major merozoite surface proteins in natural populations. Exp Parasitol 84 :92–95.
-
18
da Silveira LA, Dorta MI, Kimura E, Katzin AM, Kawamoto F, Tanabe K, Ferreira M, 1999. Allelic diversity and antibody recognition of Plasmodium falciparum merozoite surface protein-1 during hypoendemic malaria transmission in the Brazilian Amazon region. Infect Immun 67 :5906–5916.
-
19
Kimbi HK, Tetteh KKA, Polley SD, Conway DJ, 2004. Cross-sectional study of specific antibodies to a polymorphic Plasmodium falciparum antigen and of parasite antigen genotypes in school children on the slope of Mount Cameroon. Trans Rl Soc Trop Med Hyg 98 :284–289.
-
20
Conway DJ, Rosario V, Oduola AMJ, Salako LA, Greenwood BM, McBride JS, 1991. Plasmodium falciparum intragenic recombination and nonrandom association between polymorphic domains of the precursor to the major merozoite surface antigens. Exp Parasitol 73 :469–480.
-
21
Lee EAM, Flanagan KL, Odihiambo K, Reece WHH, Potter C, Bailey R, Marsh K, Pinder M, Hill AVS, Plebanski M, 2001. Identification of frequenly recognized dimorphic T-cell epitopes in Plasmodium falciparum merozoite surface protein-1 in west and east Africans: Lack of correlation of immune recognition and allelic prevalence. Am J Trop Med Hyg 64 :194–203.
-
22
Snewin VA, Herrera M, Sanchez G, Scherf A, Langsley G, Herrera S, 1991. Polymorphism of the alleles of the merozoite surface antigens MSA1 and MSA2 in Plasmodium falciparum wild isolates from Colombia. Mol Biomed Parasitol 49 :265–276.
-
23
Montoya L, Maestre A, Carmona J, Lopes D, Do Rosario V, Blair S, 2003. Plasmodium falciparum: diversity studies of isolates from two Colombian regions with different endemicity. Exp Parasitol 104 :14–19.
-
24
Ntoumi F, Contamin H, Rogier C, Bonneloy S, Trape JF, Merceteau-Puijalon O, 1995. Age-dependent carriage of multiple Plasmodium falciparum merozoite surface Antigen-2 alleles in asymptomatic malaria infections. Am J Trop Med Hyg 52 :81–88.
-
25
Takahata N, Nei M, 1990. Allelic geneology under over-dominant and frequency-dependent selection and polymorphism of major histocompatiblity complex loci. Genetics 124 :967–978.
-
26
Hughes AL, 1992. Positive selection and interallelic recombination at the merozoite surface antigen-1 (MSA-1) locus of Plasmodium falciparum.Mol Biol Evol 9 :381–393.
-
27
Ferreira MU, Kaneko O, Masatsugu K, Qing L, Kawamoto F, Tanabe K, 1998d. Allelic diversity at the merozoite surface protein-1 (MSP-1) locus in natural Plasmodium falciparum populations: a brief overview. Mem Inst Oswaldo Cruz 93 :631–638.
-
28
Ferreira MU, Ribeiro WL, Tonon AP, Kawamoto F, Rich SM, 2003. Sequence diversity and evolution of the malaria vaccine candidate merozoite surface protein-1 (MSP-1) of Plasmodium falciparum.Gene 304 :65–75.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 448 | 362 | 55 |
| Full Text Views | 330 | 20 | 3 |
| PDF Downloads | 46 | 11 | 0 |