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Cultivation of Sexually Mature Brugia malayi In Vitro
W. A. Riberu
W. A. Riberu
U.S. Naval Medical Research Unit No. 2, Jakarta Detachment, Jakarta, Indonesia
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Soeroto Atmosoedjono
Soeroto Atmosoedjono
U.S. Naval Medical Research Unit No. 2, Jakarta Detachment, Jakarta, Indonesia
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Purnomo
Purnomo
U.S. Naval Medical Research Unit No. 2, Jakarta Detachment, Jakarta, Indonesia
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S. Tirtokusumo
S. Tirtokusumo
U.S. Naval Medical Research Unit No. 2, Jakarta Detachment, Jakarta, Indonesia
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M. J. Bangs
M. J. Bangs
U.S. Naval Medical Research Unit No. 2, Jakarta Detachment, Jakarta, Indonesia
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J. K. Baird
J. K. Baird
U.S. Naval Medical Research Unit No. 2, Jakarta Detachment, Jakarta, Indonesia
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Sexually mature male and female Brugia malayi were developed from third stage larvae after 60 days in the in vitro culture system described by Franke and others in 1987 (Am J Trop Med Hyg 37: 370–375). Between 75 and 100 days in culture, many worms produced living microfilariae. Each gravid female produced 200–1,500 microfilariae/day.
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| Past two years | Past Year | Past 30 Days | |
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| Abstract Views | 784 | 460 | 57 |
| Full Text Views | 19 | 1 | 0 |
| PDF Downloads | 21 | 2 | 0 |