| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 658 | 445 | 93 |
| Full Text Views | 6 | 1 | 0 |
| PDF Downloads | 7 | 2 | 0 |
Efficacy of Metrifonate in a Highly Endemic Area of Urinary Schistosomiasis in Kenya
Katsuyuki Sato
Katsuyuki Sato
Department of Parasitology, Institute of Tropical Medicine, Nagasaki University, Japan
Search for other papers by Katsuyuki Sato in
Current site
Google Scholar
PubMed
Search for other papers by Katsuyuki Sato in
Current site
Google Scholar
PubMed
Masaaki Shimada
Masaaki Shimada
Department of Parasitology, Institute of Tropical Medicine, Nagasaki University, Japan
Search for other papers by Masaaki Shimada in
Current site
Google Scholar
PubMed
Search for other papers by Masaaki Shimada in
Current site
Google Scholar
PubMed
Shinichi Noda
Shinichi Noda
Department of Medical Zoology, Faculty of Medicine, Kagoshima University, Japan
Search for other papers by Shinichi Noda in
Current site
Google Scholar
PubMed
Search for other papers by Shinichi Noda in
Current site
Google Scholar
PubMed
Ngethe D. Muhoho
Ngethe D. Muhoho
Centre for Microbiology Research, Kenya Medical Research Institute, Ministry of Health, Kenya
Search for other papers by Ngethe D. Muhoho in
Current site
Google Scholar
PubMed
Search for other papers by Ngethe D. Muhoho in
Current site
Google Scholar
PubMed
Tatsuya Katsumata
Tatsuya Katsumata
Department of Parasitology, Institute of Tropical Medicine, Nagasaki University, Japan
Search for other papers by Tatsuya Katsumata in
Current site
Google Scholar
PubMed
Search for other papers by Tatsuya Katsumata in
Current site
Google Scholar
PubMed
Atsuo Sato
Atsuo Sato
Department of Medical Zoology, Faculty of Medicine, Kagoshima University, Japan
Search for other papers by Atsuo Sato in
Current site
Google Scholar
PubMed
Search for other papers by Atsuo Sato in
Current site
Google Scholar
PubMed
Yoshiki Aoki
Yoshiki Aoki
Department of Parasitology, Institute of Tropical Medicine, Nagasaki University, Japan
Search for other papers by Yoshiki Aoki in
Current site
Google Scholar
PubMed
Search for other papers by Yoshiki Aoki in
Current site
Google Scholar
PubMed
In a community in Kwale district, Kenya, selective mass chemotherapy with metrifonate caused a marked reduction in the intensity of Schistosoma haematobium infection from 46.5 to 9.4 eggs/hr and a sharp fall in prevalence of gross hematuria from 18.3% to 5.1%, although overall prevalence was reduced only slightly from 67.4% to 54%. The effect of metrifonate on cure rate and reduction of infection intensity was limited by both age and pretreatment infection intensity. Rate of improvement from gross hematuria was similar in all ages and in all classes of intensity of infection. Two doses of metrifonate reduced the prevalence of gross hematuria as much as 3 doses did, while the effect of a single dose on morbidity remains to be clarified.
Author Notes
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 658 | 445 | 93 |
| Full Text Views | 6 | 1 | 0 |
| PDF Downloads | 7 | 2 | 0 |