Ovaries and Adrenals in Murine Schistosomiasis Mansoni

II. Some Observations on the Function of the Ovaries in Acute Infection

T. Tiboldi Institute of Tropical Medicine Prince Leopold and Provincial Institute of Hygiene, Nationalestraat 155, B-2000 Antwerp, Belgium

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B. Colfs Institute of Tropical Medicine Prince Leopold and Provincial Institute of Hygiene, Nationalestraat 155, B-2000 Antwerp, Belgium

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M. de Smet Institute of Tropical Medicine Prince Leopold and Provincial Institute of Hygiene, Nationalestraat 155, B-2000 Antwerp, Belgium

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H. Van Soom Institute of Tropical Medicine Prince Leopold and Provincial Institute of Hygiene, Nationalestraat 155, B-2000 Antwerp, Belgium

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In mice with acute schistosomiasis mansoni the mean serum level of progesterone, as determined by radioimmunoassay, was significantly lower than in non-infected control animals, probably due to the atrophy of corpora lutea and the discontinuance of their development described in an earlier paper. In spite of the histopathological changes in the ovaries and the decreased level of progesterone in the blood, estrus was present in some infected animals.

Author Notes

Present address: Provincial Institute of Hygiene, Nationalestraat 155, B-2000 Antwerp, Belgium.

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