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An Evaluation of Passive Cutaneous Anaphylactic Reactions with Trichinella and Toxocara Antibody-Antigen Systems
Michael H. Ivey
Michael H. Ivey
Department of Preventive Medicine and Public Health, University of Oklahoma School of Medicine, Oklahoma City, Oklahoma
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Roger Slanga
Roger Slanga
Department of Preventive Medicine and Public Health, University of Oklahoma School of Medicine, Oklahoma City, Oklahoma
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Summary
The test for passive cutaneous anaphylaxis (PCA) proved relatively simple and easy to perform. Within limits, the minimal amount of challenge Trichinella antigen was dependent on the amount of antibody used for sensitization. The optimal concentrations of Trichinella and Toxocara antigens to use in PCA tests with these experimental infections were determined. Studies with rabbit and guinea pig antisera indicate that antibodies involved in PCA reactions may differ from those involved in bentonite flocculation or hemagglutination tests. PCA reactions with heterologous antigens are common. The simplicity of the procedure is considered of distinct value and advantageous, but the amount of antigen required for a reaction and the possibility of cross-reactions are drawbacks.
Author Notes
Department of Microbiology, University of Missouri, Columbia, Missouri.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 517 | 276 | 48 |
| Full Text Views | 3 | 1 | 0 |
| PDF Downloads | 2 | 2 | 0 |