1921
image of Effects of Boiling Drinking Water on Diarrhea and Pathogen-Specific Infections in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Globally, approximately 2 billion people lack microbiologically safe drinking water. Boiling is the most prevalent household water treatment method, yet evidence of its health impact is limited. To conduct this systematic review, we searched four online databases with no limitations on language or publication date. Studies were eligible if health outcomes were measured for participants who reported consuming boiled and untreated water. We used reported and calculated odds ratios (ORs) and random-effects meta-analysis to estimate pathogen-specific and pooled effects by organism group and nonspecific diarrhea. Heterogeneity and publication bias were assessed using , meta-regression, and funnel plots; study quality was also assessed. Of the 1,998 records identified, 27 met inclusion criteria and reported extractable data. We found evidence of a significant protective effect of boiling for infections (OR = 0.31, 95% confidence interval [CI] = 0.13–0.79, = 4 studies), (OR = 0.35, 95% CI = 0.17–0.69, = 3), protozoal infections overall (pooled OR = 0.61, 95% CI = 0.43–0.86, = 11), viral infections overall (pooled OR = 0.83, 95% CI = 0.7–0.98, = 4), and nonspecific diarrheal outcomes (OR = 0.58, 95% CI = 0.45–0.77, = 7). We found no evidence of a protective effect for helminthic infections. Although our study was limited by the use of self-reported boiling and non-experimental designs, the evidence suggests that boiling provides measureable health benefits for pathogens whose transmission routes are primarily water based. Consequently, we believe a randomized controlled trial of boiling adherence and health outcomes are needed.

[open-access] This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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/content/journals/10.4269/ajtmh.17-0190
2017-09-05
2017-09-23
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.17-0190
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  • Published online : 05 Sep 2017
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