image of Seroprevalence of Hepatitis E among Boston Area Travelers, 2009–2010
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


We determined the prevalence of IgG antibodies to hepatitis E virus (anti‐HEV IgG) among travelers attending Boston‐area travel health clinics from 2009 to 2010. Pre‐travel samples were available for 1,356 travelers, with paired pre‐ and post‐travel samples for 450 (33%). Eighty of 1,356 (6%) pre‐travel samples were positive for anti‐HEV IgG. Compared with participants who had never lived in nor traveled to a highly endemic country, the pre‐travel prevalence odds ratio (POR) of anti‐HEV IgG among participants born in or with a history of previous travel to a highly endemic country was increased (POR = 4.8, 95% CI = 2.3–10.3 and POR = 2.6, 95% CI = 1.4–5.0, respectively). Among participants with previous travel to a highly endemic country, anti‐HEV IgG was associated with age > 40 years (POR = 3.7, 95% CI = 1.3–10.2) and travel history to ≥ 3 highly endemic countries (POR = 2.7, 95% CI = 1.2–5.9). Two participants may have contracted HEV infection during their 2009–2010 trip.


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  • Published online : 30 Jan 2017
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